# The Experience of Women With Breast or Gynecological Cancer After Participation in an Online Mindfulness‐Based Cancer Recovery (e‐MBCR) Program: Secondary Outcomes Analysis of a Pilot Mixed Methods Randomized Controlled Trial

**Authors:** Marie‐Estelle Gaignard, Dominica Martin, Jelena Stanic, Roger Hilfiker, Alexandre Bodmer, Michael Ljuslin, Khalil Zaman, Intidhar Labidi‐Galy, Apostolos Sarivalasis, Linda E. Carlson, Solange Peters, Pierre‐Yves Dietrich, Manuela Eicher, Guido Bondolfi, Françoise Jermann

PMC · DOI: 10.1002/pon.70334 · Psycho-Oncology · 2025-11-21

## TL;DR

This study explores how women with breast or gynecological cancer experienced an online mindfulness program, finding both benefits and challenges in their recovery journey.

## Contribution

This is the first mixed methods study to examine experiences after an online mindfulness-based cancer recovery program.

## Key findings

- The intervention group showed a significant reduction in depression with a medium effect size.
- Qualitative interviews revealed themes like a safe environment, skill acquisition, and enhanced well-being.
- Some participants found the program challenging, especially when confronting cancer memories.

## Abstract

Mindfulness‐Based Interventions (MBIs) are recognized as beneficial in oncology supportive care. While qualitative analyses of mindfulness program experiences exist, this is the first mixed methods study to examine patients' experiences after participating in the online Mindfulness‐Based Cancer Recovery (e‐MBCR) program.

The SERENITY study was a pilot randomized controlled trial evaluating the early implementation, and effects of the e‐MBCR program for women with breast or gynecological cancer in a French‐speaking context. This article reports on secondary outcomes from a mixed methods analysis, exploring psychosocial aspects through questionnaires and participants' experiences through interviews. Sixty‐two patients were randomized in a 2:1 ratio. Quantitative assessments were carried out at three timepoints; qualitative interviews only post‐intervention. Both datasets were analyzed separately, then merged for interpretation.

The intervention group showed a significant reduction in depression compared to the control group, with a medium effect size post‐intervention. While other psychological measures did not show significant differences, this exploratory analysis revealed favorable trends, particularly in anxiety, spiritual well‐being, and post‐traumatic growth. At 3‐month follow‐up, most scales showed a diminished effect compared to post‐intervention. Qualitative interviews revealed four themes: a safe and validating environment, acquiring skills and taking action, enhanced well‐being, and exposure to memories of cancer. This last dimension was a source of beneficial inner work for most participants, although it was a deeply challenging experience for four women.

Participation in the e‐MBCR program led to beneficial experiences, notably self‐exploration, and enhanced self‐efficacy. However, MBIs can also bring up challenging experiences, which are important to acknowledge.

NCT04564768

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** Breast or Gynecological Cancer (MESH:D001943), Cancer (MESH:D009369), anxiety (MESH:D001007), depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

46 references — full list in the complete paper: https://tomesphere.com/paper/PMC12639194/full.md

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Source: https://tomesphere.com/paper/PMC12639194