# Front Cover

## TL;DR

This paper explores how knocking out a specific gene in mice can reduce spinal cord injury by affecting heme synthesis and a key protein activation.

## Contribution

The study introduces a novel approach using microglial SLC25A28 knockout to mitigate spinal cord injury in mice.

## Key findings

- SLC25A28 knockout in microglia reduces spinal cord injury in mice.
- The knockout inhibits heme synthesis and subsequent NOX2 activation.

## Abstract

The cover image is based on the article Microglial SLC25A28 Knockout Mitigates Spinal Cord Injury in Mice by Inhibiting Heme Synthesis and Subsequent NOX2 Activation by Huangtao Chen et al., https://doi.org/10.1111/cns.70638.