# The 7 C Vaccination Readiness Scale: An Empirical Country Comparison Between Germany and Greece

**Authors:** Birgit Teichmann, Ioannis Ladas, Demosthenes B. Panagiotakos

PMC · DOI: 10.1007/s44197-025-00485-9 · Journal of Epidemiology and Global Health · 2025-11-21

## TL;DR

This study validates a psychological scale for measuring vaccination readiness in Germany and Greece, finding differences in attitudes and behaviors.

## Contribution

The study validates the 7 C scale for vaccination readiness in German and Greek populations and identifies cross-cultural differences.

## Key findings

- The 7 C scale showed acceptable psychometric properties in both German and Greek samples.
- German participants had higher vaccination rates except for hepatitis A, varicella, and meningococcal disease.
- The scale's components confidence, complacency, and conspiracy showed significant differences between the two countries.

## Abstract

Vaccinations are among the most effective interventions against infectious diseases such as measles, influenza, and COVID-19. Nevertheless, there are significant differences in vaccination readiness. The aim of this study was to validate the 7 C scale, which measures seven psychological factors comprising general vaccination readiness, in both German and Greek, and to investigate differences in vaccination behavior between a German and a Greek sample.

A cross-sectional study was conducted with a convenience sample of 576 study participants, of whom 319 responded to the online survey in German and 257 in Greek. Analyses included internal consistency, structural validity, construct validity through the known-groups method, item analysis, and floor and ceiling effects. The two samples differed significantly in terms of demographic data such as age, gender and education, as well as in religiosity and vaccination behavior.

The German sample showed a higher vaccination rate for most vaccinations, except for vaccinations against hepatitis A, varicella, and meningococcal disease, wheras in the Greek sample, there were significantly more “I don’t know” responses regarding vaccination status. The 7 C scale of vaccination readiness demonstrated acceptable to good psychometric properties in terms of both internal consistency and construct validity in both samples, although there were some weaknesses in the component that measures calculationR in both the 21-item and 7-item versions. The 7-component structure was confirmed using a confirmatory factor analysis. The German and the Greek samples differ primarily in the components confidence, complacencyR, and conspiracyR, with significantly higher values in the German sample. Binary logistic regression analysis demonstrated that the 7 C scale had the lowest predictive value for measles vaccination and the highest for COVID-19.

The German and Greek versions of the 7 C scale are invaluable research tools for investigating vaccination readiness. A comprehensive understanding of the underlying factors contributing to vaccine hesitancy is imperative for the development of culturally tailored educational initiatives. These initiatives must be designed to address prevalent misconceptions regarding vaccination, with the objective of enhancing vaccination rates, and promoting public health.

The online version contains supplementary material available at 10.1007/s44197-025-00485-9.

## Linked entities

- **Diseases:** measles (MONDO:0004619), influenza (MONDO:0005812), COVID-19 (MONDO:0100096), hepatitis A (MONDO:0005790), varicella (MONDO:0005700), meningococcal disease (MONDO:0005373)

## Full-text entities

- **Diseases:** varicella (MESH:D002644), hepatitis A (MESH:D056486), meningococcal disease (MESH:D008589), measles (MESH:D008457), COVID-19 (MESH:D000086382), influenza (MESH:D007251), infectious diseases (MESH:D003141)

## Full text

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## Figures

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12638586/full.md

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Source: https://tomesphere.com/paper/PMC12638586