# The Effect of Acerola Intake on Metabolic and Immunological Parameters in Elite Athletes

**Authors:** Libor Vítek, Jana Hajšlová, Miloš Bátovský, Jana Woronyczová, Helena Posová, Miroslava Zelenková, Jaroslav Pilný, Marta Kalousová

PMC · DOI: 10.1007/s11130-025-01434-4 · Plant Foods for Human Nutrition (Dordrecht, Netherlands) · 2025-11-21

## TL;DR

This study explores how acerola fruit affects metabolism and immunity in elite athletes, finding potential benefits for metabolic flexibility and inflammation.

## Contribution

The study is the first to investigate acerola's effects on immune and metabolic parameters in elite athletes.

## Key findings

- Acerola supplementation decreased serum immunoglobulin concentrations and inflammatory markers.
- Acerola significantly reduced serum glucose, urea, and liver enzymes ALT and AST.
- Acerola may improve metabolic flexibility and low-grade inflammatory status in elite athletes.

## Abstract

Acerola is an edible tropical fruit known for its high antioxidant activity. It is recommended as a superfood to improve general health. However, its role in elite sport has not been studied in detail so far. Therefore, the objective of the study was to assess the effect of regular use of acerola on parameters of the immune system, oxidative stress, and metabolism in elite athletes. The study was carried out in 22 elite endurance athletes (mean age = 24.4 ± 4 years; M:F ratio = 1.75), who were supplemented with acerola pulp at a dose of 300 g/day for 3 weeks. Detailed laboratory studies, including analyses of biochemical, hematological, and immunological parameters, were carried out in all subjects before and after acerola supplementation. Acerola supplementation did not change any tested parameters of oxidative stress but decreased serum immunoglobulin concentrations and some inflammatory markers. Simultaneously, acerola significantly decreased serum glucose, urea, and liver enzymes ALT and AST, suggesting its role in modulating metabolic flexibility. Acerola supplementation appears to play a beneficial role in elite endurance sports by improving low-grade inflammatory status and metabolic flexibility. Long-term, larger studies are needed to confirm current data and the possible impact on sports performance, as well as to assess any side effects of chronic use.

## Full-text entities

- **Genes:** SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}
- **Diseases:** inflammatory (MESH:D007249)
- **Chemicals:** glucose (MESH:D005947), urea (MESH:D014508), acerola pulp (-)
- **Species:** Malpighia glabra (species) [taxon 71611]

## Full text

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Source: https://tomesphere.com/paper/PMC12638340