# Evaluation of a “one-stop shop” for integrated harm reduction and primary care for people who inject drugs

**Authors:** Nadeen Ibrahim, Shaifer Jones, Katherine Rich, Lisandra Alvarez, Carolina Price, Natalie Kil, Frederick L. Altice, Jaimie P. Meyer

PMC · DOI: 10.1371/journal.pone.0337528 · PLOS One · 2025-11-21

## TL;DR

This study evaluates a comprehensive harm reduction program for people who inject drugs, showing it effectively serves a large and diverse population.

## Contribution

The paper presents the first comprehensive analysis of a large SSP through the COVID-19 pandemic, highlighting its service reach and client characteristics.

## Key findings

- The SSP served 1,189 unique individuals, with most identifying as men and white, and an average age of 41.
- The program dispensed over 1.8 million syringes and provided overdose education and naloxone during the pandemic.
- Client utilization increased during the pandemic, indicating high demand for on-demand harm reduction services.

## Abstract

People who inject drugs (PWID) experience high risk for HIV and HCV infection, which can be mitigated by harm reduction strategies, including syringe service programs (SSP). Understanding individuals’ patterns of substance use and SSP utilization is important for optimizing harm reduction strategies and disease prevention for PWID.

We evaluated demographic characteristics and service utilization from the New Haven Syringe Services Program (NHSSP), a low-threshold service delivery site in New Haven, Connecticut that provides fully integrated harm reduction and primary healthcare services to PWID. Site-specific data were extracted from the e2ctprevention database, managed by the Connecticut Department of Public Health, and EvaluationWeb from January 2017 to October 2023. We conducted a descriptive analysis of basic demographic and social characteristics of SSP clients, transaction characteristics, and service utilization. Statistical analyses were conducted using STATA v 16.1 and IBM SPSS Statistics (v 29.0.2.0).

Among 1,189 unique individuals utilizing SSP during the observation period, most (65.2%) identified as men and white (73.3%), consistent with SSP clients regionally and nationally. The mean age of clients was 41 years (SD = 9.8); approximately half of participants were unstably housed and 80% were unemployed at intake. From June 2020 to October 2023, there were 7,238 transactions, which increased throughout the COVID-19 pandemic period. During this period, the program dispensed 1,860,621 syringes, in addition to other materials, including overdose education and naloxone distribution (OEND), and provided patient education on safer injecting techniques and wound care.

In this first comprehensive analysis of a large SSP since its inception and through the COVID-19 pandemic, we described important client characteristics and utilization of an array of syringe services from an integrated SSP. Findings suggest the SSP attracts a high volume of clients, provides on-demand services, and reaches a wide range of clients. Future research is needed to evaluate the impact of the program’s home-delivery service and increased outreach efforts. Despite limitations, the program’s success demonstrates the SSP can serve as a model for other harm reduction programs nationally.

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), overdose (MESH:D062787), HIV and HCV infection (MESH:D015658)
- **Chemicals:** naloxone (MESH:D009270)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12637901/full.md

## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12637901/full.md

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Source: https://tomesphere.com/paper/PMC12637901