# Solitary plasmacytoma of the skull compressing the superior sagittal sinus: Case report and literature review

## TL;DR

A rare case of skull plasmacytoma compressing a brain vein is reported, emphasizing the importance of accurate diagnosis and successful surgical treatment.

## Contribution

A detailed case report and literature review highlighting diagnostic challenges and successful surgical management of a rare intracranial plasmacytoma.

## Key findings

- Total surgical resection led to a favorable 40-month outcome without recurrence.
- A literature review identified 14 similar cases involving superior sagittal sinus compression.
- Diagnostic differentiation from common dural-based tumors requires radiologic and histopathologic evaluation.

## Abstract

Solitary plasmacytomas are rare, localized plasma cell neoplasms without systemic involvement. Intracranial manifestations, particularly those compressing the superior sagittal sinus, are exceptionally uncommon and can mimic more common dural-based lesions such as meningiomas.

This study aims to highlight the diagnostic and therapeutic considerations in cases of intracranial solitary plasmacytoma involving superior sagittal sinus compression through a clinical case and a targeted literature review.

We report a case of a 52-year-old male who presented with progressive skull swelling as the only symptom. Due to the lesion's pronounced mass effect and marked compression of the superior sagittal sinus, a craniotomy and complete surgical resection were performed. A systematic literature search was conducted via PubMed to identify previously reported cases of intracranial solitary plasmacytoma involving superior sagittal sinus compression.

In the present case, histopathological examination confirmed the diagnosis of solitary plasmacytoma and surgical resection alone resulted in a favorable clinical outcome without recurrence during a 40-month follow-up. Our systematic review identified 14 patients with intracranial solitary plasmacytoma causing superior sagittal sinus compression across 12 published articles.

Differentiation from more common intracranial lesions is crucial and relies on careful radiologic and histopathologic evaluation. Solitary plasmacytoma should be considered in the differential diagnosis of dural-based lesions involving venous sinuses. Further studies and clinical reports are essential to clarify prognostic factors and to refine therapeutic strategies for this rare entity.

•Intracranial solitary plasmacytoma compressing the superior sagittal sinus is exceedingly rare.•The lesion presented with features resembling common dural-based intracranial tumors.•Total surgical resection led to excellent 40-month outcome without any recurrence.•Literature review identified 14 similar cases with compression of the superior sagittal sinus.•Radiologic and histopathologic features guiding differential diagnosis are detailed.

Intracranial solitary plasmacytoma compressing the superior sagittal sinus is exceedingly rare.

The lesion presented with features resembling common dural-based intracranial tumors.

Total surgical resection led to excellent 40-month outcome without any recurrence.

Literature review identified 14 similar cases with compression of the superior sagittal sinus.

Radiologic and histopathologic features guiding differential diagnosis are detailed.