# Targeting inflammasome pathway towards therapeutics of neurodegenerative diseases

## TL;DR

This paper reviews how targeting the inflammasome pathway could lead to new treatments for neurodegenerative diseases.

## Contribution

The paper provides a comprehensive review of inflammasome's role in neurodegeneration and current therapeutic strategies.

## Key findings

- Inflammasome activation is significantly involved in the pathology of neurodegenerative diseases.
- Targeting the inflammasome pathway is a promising therapeutic strategy for these diseases.

## Abstract

Inflammasome, an intracellular protein complex, is a crucial regulator of the innate immune response defending against harmful insults. Increasing evidence indicates that activation of inflammasome pathway in brain cells plays a significant pathological role in neurodegenerative diseases. Targeting this pathway offers a promising strategy for developing novel treatments. Here, we review the wide-ranging involvement of inflammasome activation in neurodegenerative diseases and highlight current therapeutic strategies targeting this critical pathway.