# Correlation study of fatty pancreas and fatty liver CT manifestations with biochemical parameters in middle-aged and young adult cholecystectomy patients

## TL;DR

This study found that cholecystectomy is linked to higher rates of fatty pancreas, especially compared to fatty liver, in middle-aged and young adults.

## Contribution

The study identifies a significant association between cholecystectomy and increased pancreatic steatosis.

## Key findings

- Cholecystectomy patients had higher rates of pancreatic and hepatic steatosis compared to controls.
- Pancreatic steatosis was significantly associated with cholecystectomy, but not hepatic steatosis.
- Post-cholecystectomy patients should be monitored for pancreatic steatosis to enable early intervention.

## Abstract

To investigate the correlation between the occurrence of pancreatic steatosis, hepatic steatosis, and cholecystectomy, as well as the associated biochemical parameters.

A retrospective analysis was conducted on 409 patients who underwent abdominal CT scans between November 2022 and March 2024. Among them, 127 patients had undergone cholecystectomy (experimental group), while 282 had not (control group). The incidence rates of pancreatic steatosis and hepatic steatosis were compared between the two groups, along with relevant biochemical parameters including total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and fasting blood glucose levels.

The incidence of pancreatic steatosis in the experimental group was 67.8%, and the incidence of hepatic steatosis was 22%. In the control group, the incidence rates were 54.3% for pancreatic steatosis and 15.6% for hepatic steatosis. The rates of both pancreatic and hepatic steatosis significantly increased following cholecystectomy, with pancreatic steatosis showing a notably higher incidence than hepatic steatosis. Statistical analysis revealed a significant correlation between cholecystectomy and pancreatic steatosis (p < 0.05), whereas no significant correlation was found with hepatic steatosis.

The incidence rates of both pancreatic and hepatic steatosis are elevated following cholecystectomy, particularly for pancreatic steatosis. The study indicates a significant association between cholecystectomy and pancreatic steatosis. Therefore, it is recommended to closely monitor patients who have undergone cholecystectomy for the development of pancreatic steatosis, allowing for early diagnosis and intervention to prevent the progression of related conditions.