# Factors Affecting Hospital Stay Duration in the Conservative Treatment of Patients With Osteoporotic Vertebral Fractures

**Authors:** Koshiro Shimasaki, Kousei Miura, Tomohiro Yoshizawa, Tomofumi Nishino, Harumitsu Ichimura, Masafumi Uesugi, Hajime Mishima

PMC · DOI: 10.7759/cureus.95127 · Cureus · 2025-10-22

## TL;DR

This study identifies factors like cognitive impairment and mobility that affect how long patients with osteoporotic vertebral fractures stay in the hospital during conservative treatment.

## Contribution

The study provides new insights into modifiable factors influencing hospital stay duration and discharge outcomes in patients with osteoporotic vertebral fractures.

## Key findings

- Cognitive impairment, pre-injury mobility, cohabitation status, and in-hospital complications significantly affect hospital stay duration.
- Patients with cognitive impairment are less likely to be discharged home and more likely to go to non-home settings.
- Early multidisciplinary intervention targeting these factors can improve discharge outcomes and reduce hospital stays.

## Abstract

Introduction: Our research question explores the factors contributing to the substantial variation in the length of hospital stay among patients receiving inpatient conservative treatment for osteoporotic vertebral fractures (OVFs). This study aimed to identify key determinants influencing hospitalization duration in this patient population.

Methods: Overall, 187 patients admitted for conservative treatment of OVF at a single institution between April 2020 and March 2024 were retrospectively analyzed. Data on age, sex, Charlson Comorbidity Index (CCI), cognitive impairment, pre-injury mobility, cohabitation status, in-hospital complications, nutritional status, sarcopenia, discharge destination, and length of stay were obtained. A subgroup analysis was conducted to compare patients discharged home with those discharged to non-home settings.

Results: Multiple regression analysis revealed that cognitive impairment, pre-injury mobility, cohabitation status, and in-hospital complications significantly influenced the length of stay. In the subgroup analysis, sex and cognitive impairment were significant in the univariate analysis, whereas cognitive function remained significant in the multivariate analysis.

Conclusions: Inpatients with OVFs undergoing conservative treatment had a significantly longer length of stay if they had cognitive impairment, lower pre-injury mobility, lived alone, or experienced hospitalization-related complications. Patients with cognitive impairment were less likely to be discharged home but more likely to be discharged to non-home settings, including care facilities. Early intervention by a multidisciplinary team targeting these factors can increase home-discharge rates, reduce length of stay, lower medical costs, and extend healthy life expectancy.

## Full-text entities

- **Diseases:** Comorbidity (MESH:D004194), OVFs (MESH:D058866), sarcopenia (MESH:D055948), cognitive impairment (MESH:D003072)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12635891/full.md

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Source: https://tomesphere.com/paper/PMC12635891