# Case Report: 18F-Fluorocholine PET/CT for detecting brown tumours in patients with hyperparathyroidism: a short case series and literature review

## TL;DR

This case series explores using 18F-fluorocholine PET/CT to detect brown tumours in hyperparathyroidism patients.

## Contribution

Demonstrates the potential of FCH PET/CT as a novel imaging tool for brown tumours in hyperparathyroidism.

## Key findings

- FCH PET/CT successfully detected brown tumours in three hyperparathyroidism cases.
- Literature review supports FCH PET/CT as a promising technique for BT detection.
- Further studies are needed to validate FCH PET/CT's role in BT diagnosis.

## Abstract

Brown tumours (BTs), also known as osteitis fibrosa cystica, are benign osteolytic lesions associated with hyperparathyroidism (HPT). BTs are cured by correcting the hypercalcaemia and HPT, which often requires surgical resection of the parathyroid adenoma. 1⁸F-fluorocholine (FCH) PET/CT is becoming an effective tool for detecting parathyroid adenomas in cases of hyperparathyroidism. This study aims to evaluate the role of FCH PET/CT in detecting brown tumours in patients with hyperparathyroidism.

Three cases are presented to demonstrate the effectiveness of FCH PET/CT in detecting BTs in patients presenting with clinical and biochemical signs of HPT with suspicion of BTs.

A literature review aimed to summarize the bibliographic evidence on the use of this technique in this setting, which is relatively innovative.

FCH PET/CT appears to be a useful tool for detecting BTs, and further prospective studies are needed to confirm this.