# Fixing a Mismatch: The Case for Age-Aligned Kidney Allocation

**Authors:** Emmanouil Giorgakis, Sorabh Kapoor, Esteban Calderon, Melissa Chen, Kunal Kapoor, Alex Toledo, Chirag S. Desai

PMC · DOI: 10.3389/ti.2025.15148 · Transplant International · 2025-11-07

## TL;DR

This paper argues for adjusting kidney transplant allocation to better match donor and recipient ages, aiming to improve fairness and efficiency in organ distribution.

## Contribution

The paper proposes age-aligned kidney allocation as a novel approach to enhance equity and utility in deceased donor kidney transplants.

## Key findings

- Current allocation strategies do not adequately consider donor-recipient age mismatches.
- Age-matched allocation could reduce organ discard rates and improve long-term graft outcomes.
- Revising kidney donor risk calculators and capping preemptive wait-time may enhance transplant sustainability.

## Abstract

Despite recent advances, deceased donor kidney transplant allocation in the United States does not sufficiently account for the mismatch between donor and recipient age. This misalignment often leads to a suboptimal use of scarce resources. This viewpoint calls for restructuring of current kidney allocation strategies, advocating for a more intentional, age-matched approach that prioritizes better long-term quality kidneys for proportionally younger patients and encourages the use of older donor kidneys in similarly aged recipients. Drawing on the National Scientific Registry of Transplant Recipients data, clinical observations, and ethical reasoning, we argue that incorporating age in the organ allocation algorithms may improve both equity and utility in organ distribution. We also advocate for revision of the kidney donor risk calculators and placing a cap on the pre-emptive wait-time. Such realignments may reduce organ discard rates, enhance long-term graft utility, alleviate decision-making burdens on patients, and decrease the need for re-transplants on younger patients. To achieve this, recalibrations in allocation algorithms and reframing of what constitutes a “good” kidney are required. The goal is not to limit choice, but to structure a framework that maximizes benefit across populations while maintaining fairness towards a more sustainable model of transplant care.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12634456/full.md

## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12634456/full.md

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Source: https://tomesphere.com/paper/PMC12634456