# More Than Just a Plaque: A Diagnostic Challenge in a Case of Suspected Cutaneous Localized Nodular Amyloidosis

## TL;DR

A rare skin condition called PLCNA was diagnosed through histopathology in a case that initially resembled more common skin diseases.

## Contribution

Highlights the importance of histopathological diagnosis for PLCNA in resource-limited settings where advanced tests are unavailable.

## Key findings

- PLCNA presented as a solitary facial plaque mimicking common dermatoses.
- Histopathology confirmed PLCNA in the absence of Congo Red staining.
- Early diagnosis is crucial to monitor for potential systemic involvement.

## Abstract

Primary Localized Cutaneous Nodular Amyloidosis (PLCNA) can rarely present on the face and may mimic more common dermatoses. In such atypical cases, especially in resource‐limited settings where confirmatory tests like Congo Red staining are unavailable, histopathological examination is crucial for diagnosis. Early recognition is vital for proper management and monitoring for potential systemic involvement.

A solitary facial nodular plaque clinically mimicking common dermatoses, diagnosed as Primary Localized Cutaneous Nodular Amyloidosis (PLCNA) through histopathology in a resource‐limited setting.