# Successful Treatment of Delayed Partial Flap Loss in Autologous Breast Reconstruction With Rivaroxaban

**Authors:** Jadon H Beck, Anne M Meyer, Kerilyn Godbe, James A Butterworth, Eric C Lai

PMC · DOI: 10.7759/cureus.95094 · Cureus · 2025-10-21

## TL;DR

A 72-year-old woman's breast reconstruction flap congestion was successfully treated with rivaroxaban, suggesting anticoagulation may help in such cases.

## Contribution

This is the first reported case suggesting systemic anticoagulation may salvage delayed partial flap congestion in breast reconstruction.

## Key findings

- A patient with partial flap congestion showed improvement after three weeks of rivaroxaban treatment.
- The case suggests systemic anticoagulation could be a novel salvage strategy for delayed flap complications.
- No prior literature documents anticoagulation use for this specific postoperative complication.

## Abstract

Modern free flap breast reconstruction has high levels of success and patient satisfaction. When delayed microvascular complications do arise, corresponding salvage rates are low. Here, we present the case of a 72-year-old female who underwent uneventful right autologous breast reconstruction using profunda artery perforator (PAP) stacked flaps, whose course was complicated at postoperative day eight by partial superior flap congestion. Successful salvage of the superior PAP flap was achieved after three weeks of rivaroxaban treatment. To our knowledge, this case is the first in the literature to suggest the potential benefit of systemic anticoagulation in treating delayed partial flap congestion.

## Linked entities

- **Chemicals:** rivaroxaban (PubChem CID 6433119)

## Full-text entities

- **Diseases:** Flap Loss (MESH:D000070600)
- **Chemicals:** Rivaroxaban (MESH:D000069552)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12634056/full.md

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Source: https://tomesphere.com/paper/PMC12634056