# Cervical Tuberculosis in the Postmenopausal Period: A Case of Mistaken Identity With Carcinoma

**Authors:** Nafisa M El Sunni, Sara Adam, Saadia A Noreldeen, Mohamed Y Adam

PMC · DOI: 10.7759/cureus.97336 · Cureus · 2025-11-20

## TL;DR

A postmenopausal woman with cervical tuberculosis was initially mistaken for having cervical cancer, emphasizing the need for accurate diagnosis in endemic regions.

## Contribution

This case highlights the rarity and diagnostic challenge of isolated cervical tuberculosis mimicking gynecological cancer.

## Key findings

- Histopathological analysis confirmed tuberculosis in a patient initially suspected of cervical cancer.
- The patient showed significant clinical improvement after a six-month anti-tuberculosis treatment.
- Cervical tuberculosis should be considered in the differential diagnosis for postmenopausal pelvic symptoms in endemic areas.

## Abstract

Female genital tuberculosis (FGTB) is an uncommon manifestation of extrapulmonary tuberculosis that can closely resemble gynaecological malignancies, often resulting in delayed diagnosis and treatment. While the fallopian tubes are the commonest organs to be affected, isolated cervical involvement is exceedingly rare. We report the case of a 60-year-old multiparous woman from a tuberculosis-endemic region in Sudan who presented with severe lower abdominal, pelvic, and perineal pain, along with odourless vaginal discharge persisting for four months. Her condition had rendered her bedridden. Clinical examination revealed a nodular cervix, initially suggestive of cervical cancer. However, histopathological analysis of cervical and endometrial biopsies confirmed caseating granulomas indicative of tuberculosis. The patient had no prior history of tuberculosis or malignancy and had never undergone cervical cancer screening. Imaging showed a uterocervical mass without signs of spinal or metastatic disease, and pulmonary tuberculosis was ruled out via chest X-ray and sputum analysis. She was treated with a standard six-month anti-tuberculosis regimen, resulting in significant clinical improvement and restored mobility. This case highlights the importance of considering cervical tuberculosis in the differential diagnosis of postmenopausal women presenting with pelvic symptoms in endemic areas. Early histological diagnosis and timely initiation of therapy are crucial for favourable outcomes.

## Linked entities

- **Diseases:** female genital tuberculosis (MONDO:0006758), tuberculosis (MONDO:0018076), cervical cancer (MONDO:0002974)

## Full-text entities

- **Diseases:** pelvic symptoms (MESH:D010386), cervical cancer (MESH:D002583), abdominal, pelvic, and perineal pain (MESH:D015746), granulomas (MESH:D006099), pulmonary tuberculosis (MESH:D014397), spinal (MESH:D013122), cervix (MESH:D002577), FGTB (MESH:D014384), Carcinoma (MESH:D009369), extrapulmonary tuberculosis (MESH:D000092225), metastatic disease (MESH:D000092182), Cervical Tuberculosis (MESH:D014376)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12634053/full.md

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Source: https://tomesphere.com/paper/PMC12634053