# Distinguishing Acute Pancreatitis From Refractory Peritonitis in Peritoneal Dialysis: A Case Report

**Authors:** Joaquim Milheiro, Raquel Pinto, Cátia Pêgo, Tania Sousa, Sérgio Lemos

PMC · DOI: 10.7759/cureus.95093 · Cureus · 2025-10-21

## TL;DR

A case report describes a patient on peritoneal dialysis who developed acute pancreatitis, highlighting the importance of accurate diagnosis and monitoring.

## Contribution

The report provides a detailed case of acute pancreatitis in a PD patient, emphasizing diagnostic challenges and monitoring techniques.

## Key findings

- A 60-year-old woman on PD presented with acute pancreatitis symptoms and elevated pancreatic enzymes.
- Exclusion of classical pancreatitis causes was critical for accurate diagnosis.
- Peritoneal effluent evaluation proved essential in monitoring the patient's condition.

## Abstract

Patients undergoing peritoneal dialysis (PD) are at increased risk for acute pancreatitis, a rare but potentially fatal disease that arises from still poorly understood mechanisms. We report the case of a 60-year-old woman on PD admitted to the emergency room with severe epigastric pain, nausea, and emesis. The patient, suffering from stage 5 chronic kidney disease (CKD) secondary to autosomal dominant polycystic kidney disease, was undergoing treatment for PD-related peritonitis. She presented on day 17 of peritonitis treatment with a cloudy peritoneal effluent and elevated pancreatic enzymes. Exclusion of classical etiologies for pancreatitis was key in ensuring an accurate diagnosis. A thorough anamnesis may identify possible triggers or risk factors involved in the development of this pathology. Peritoneal effluent evaluation is one of the most trustworthy monitoring tools. Knowledge of similar cases is warranted to further understand how we can foresee or even prevent some of these episodes, as well as their complications.

## Linked entities

- **Diseases:** acute pancreatitis (MONDO:0006515), autosomal dominant polycystic kidney disease (MONDO:0004691), peritonitis (MONDO:1010128)

## Full-text entities

- **Diseases:** emesis (MESH:D014839), nausea (MESH:D009325), epigastric pain (MESH:D010146), Peritonitis (MESH:D010538), CKD (MESH:D051436), autosomal dominant polycystic kidney disease (MESH:D016891), Acute Pancreatitis (MESH:D010195)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12634039/full.md

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Source: https://tomesphere.com/paper/PMC12634039