# Inconsistent Pulse Oximetry Signal in Multiple Sites as an Early Indicator of Severe Hypovolemia

**Authors:** Mohamad Taha, Raafay Malik, William T Davis, Sharif Mohamed

PMC · DOI: 10.7759/cureus.95085 · Cureus · 2025-10-21

## TL;DR

Poor pulse oximetry signals from multiple sites may signal severe hypovolemia, a preventable risk for shock.

## Contribution

Highlights inconsistent pulse oximetry as a potential early indicator of hypovolemia in the perioperative setting.

## Key findings

- Low-quality pulse oximetry signals from multiple sites may indicate severe hypovolemia.
- This non-invasive sign could help prevent acute decompensation during anesthesia.

## Abstract

A low-quality pulse oximetry signal should not be overlooked, as this may indicate cases of severe hypovolemia. Although this sign is not specific for volume depletion, it can provide a quick, non-invasive indication about possible hypovolemia if a proper signal cannot be obtained, especially when difficulties are encountered in obtaining SpO2 readings from multiple sites. Severe hypovolemia is a preventable risk factor for shock and other electrolyte abnormalities, which, if untreated, may lead to cardiovascular collapse or even necessitate cardiopulmonary resuscitation (CPR). This case report highlights the potential usefulness of a pulse oximeter's poor signal in multiple sites in helping providers detect volume depletion in the perioperative setting, which could prevent avoidable causes of acute decompensation during anesthetic induction.

## Full-text entities

- **Diseases:** shock (MESH:D012769), volume depletion (MESH:C536350), electrolyte abnormalities (MESH:D014883), Hypovolemia (MESH:D020896), cardiovascular collapse (MESH:D002318)

## Full text

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12634016/full.md

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Source: https://tomesphere.com/paper/PMC12634016