# Polyneuritis cranialis following actinomycosis of a wisdom tooth: a case report

**Authors:** Anna Maria Welzel, Mariya Kondova, Norbert Pfeiffer, Joanna Wasielica-Poslednik

PMC · DOI: 10.1186/s13256-025-05654-9 · 2025-11-19

## TL;DR

An 84-year-old woman developed severe eye complications due to a rare condition caused by actinomycosis of a wisdom tooth.

## Contribution

This is the first reported case of multiple cranial nerve paralysis from actinomycosis requiring ophthalmological intervention.

## Key findings

- Actinomycosis of a wisdom tooth led to polyneuritis cranialis and neurotrophic keratopathy.
- The patient required penetrating keratoplasty and amniotic membrane transplantation after conservative treatment failed.
- Computed tomography and MRI confirmed the diagnosis of actinomycosis.

## Abstract

Polyneuritis cranialis is a rare condition than can be caused by various diseases. We report the first case of multiple cranial nerve paralysis resulting in neurotrophic keratopathy with corneal ulceration as a sequel of polyneuritis cranialis due to actinomycosis.

An 84-year-old German woman developed corneal ulceration with a high risk of perforation because of neurotrophic keratopathy due to polyneuritis cranialis. Actinomycosis of a wisdom tooth causing polyneuritis cranialis was detected on computed tomography and magnetic resonance imaging and was treated with systemic antibiotics. Penetrating keratoplasty with simultaneous amniotic membrane transplantation was performed successfully after conservative treatment failure.

To the best of our knowledge, we report on the first case of multiple cranial nerve failure due to actinomycosis and requiring ophthalmological intervention.

## Linked entities

- **Diseases:** actinomycosis (MONDO:0005631), neurotrophic keratopathy (MONDO:0015290)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** Actinomycosis (MESH:D000196), multiple cranial nerve failure (MESH:D051437), corneal ulceration (MESH:D003320), Polyneuritis cranialis (MESH:D009443), neurotrophic keratopathy (MESH:C562399), multiple cranial nerve paralysis (MESH:D003389)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12632100/full.md

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Source: https://tomesphere.com/paper/PMC12632100