# Right ventricular dysfunction in structural tricuspid interventions

**Authors:** Jonathan Lee, Eirini Beneki, Nikolaos Katsanakis, Edoardo Zancanaro, Monica Mukherjee, Edgar Argulian, Julia Grapsa

PMC · DOI: 10.1093/ehjimp/qyaf135 · 2025-10-29

## TL;DR

This review discusses the importance of understanding right heart dysfunction in the context of tricuspid valve interventions and highlights current assessment tools and future directions.

## Contribution

The paper provides a synthesis of current knowledge on right heart anatomy and physiology in the context of transcatheter tricuspid valve interventions.

## Key findings

- Right heart dysfunction is commonly observed before and after TTVI and is linked to poor clinical outcomes.
- The review integrates findings from major studies on TTVI and discusses available tools for predicting patient outcomes.
- Recommendations from the Tricuspid Valve Academic Research Consortium and recent imaging parameters are highlighted.

## Abstract

With the growing global adoption of transcatheter tricuspid valve intervention (TTVI) and the increasing number of available devices, a comprehensive understanding of right heart dysfunction has become essential. Right heart dysfunction is frequently observed both before and after TTVI and is associated with adverse clinical outcomes. Therefore, a thorough understanding of right heart anatomy and physiology is critical for accurately assessing its pathological states. This review synthesizes current knowledge by integrating findings from major landmark studies on TTVI, with a focus on the available assessment tools for predicting patient outcomes. The anatomy section systematically reviews each component of the right heart—the right atrium, right ventricle, tricuspid valve, and pulmonary valve —while the physiology section emphasizes microstructural characteristics and the pressure-volume relationships. In addition, recommendations from the Tricuspid Valve Academic Research Consortium and the imaging parameters used in recent studies are discussed. Finally, future directions for imaging-based assessment of right heart function in the context of TTVI are highlighted.

## Full-text entities

- **Diseases:** Right ventricular dysfunction (MESH:D018497), Right heart dysfunction (MESH:D006331)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12631779/full.md

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Source: https://tomesphere.com/paper/PMC12631779