# Resting right ventricular function in pectus excavatum: do haller index and age matter?

## TL;DR

This study found that the Haller index and age do not significantly affect resting right ventricular function in patients with pectus excavatum.

## Contribution

The study challenges the use of Haller index and age as predictors of right ventricular dysfunction in pectus excavatum.

## Key findings

- Haller index and age showed no significant correlation with right ventricular systolic function metrics.
- Subgroup and regression analyses confirmed that neither HI nor age predicted impaired RV function.
- ROC analysis showed poor discriminatory power of age for reduced fractional area change.

## Abstract

Pectus excavatum (PE) is associated with compression of intrathoracic structures, potentially impairing right ventricular (RV) function. The Haller index (HI) is widely used to quantify the severity of deformities; however, its functional correlation remains uncertain. This study aimed to evaluate whether HI and patient age were associated with resting RV systolic function in patients with PE.

This retrospective cohort study analyzed 67 patients with PE who underwent surgical correction and had complete preoperative echocardiographic data between January 2013 and January 2024. RV function was assessed using the fractional area change (FAC) and tricuspid annular plane systolic excursion (TAPSE). Patients were stratified by HI severity (<3.2, 3.2–3.4, ≥3.5) and age (≤13 vs. >13 years). Receiver operating characteristic (ROC) analysis and multivariate regression were used to determine predictors of RV dysfunction.

The mean HI was 4.09 (±0.99), and the mean age was 15.85 (±4.96) years. Neither HI nor age significantly correlated with FAC (HI: r = –0.04, p = 0.749; age: r = 0.09, p = 0.455) or TAPSE (HI: r = –0.05, p = 0.685; age: r = 0.14, p = 0.245). Subgroup and regression analyses confirmed that neither HI nor age were predictive of impaired RV systolic function. ROC analysis demonstrated the poor discriminatory power of age for reduced FAC (area under the curve = 0.478).

Resting RV systolic function was not significantly influenced by HI or age in patients with PE. These findings highlight the need for a functional, individualized approach beyond anatomical metrics for surgical evaluation.