# Finding a Diagnosis in Obscure Gastrointestinal Bleeding: A Case of Small Bowel Neuroendocrine Tumor

**Authors:** Lin Deng, Rahul Vasavada, Christofer Bello

PMC · DOI: 10.7759/cureus.95034 · 2025-10-21

## TL;DR

This paper presents a case where advanced diagnostic tools helped identify an early-stage small bowel tumor causing obscure gastrointestinal bleeding in a 90-year-old patient.

## Contribution

The paper highlights the successful use of video capsule endoscopy and double balloon enteroscopy in diagnosing an early-stage small bowel neuroendocrine tumor.

## Key findings

- Advanced diagnostic techniques identified an early-stage jejunal-ileum neuroendocrine tumor causing GI bleeding.
- Timely surgical intervention was possible due to the use of video capsule endoscopy and double balloon enteroscopy.
- Early-stage small bowel tumors are often undetected until they metastasize, but recent innovations improve early diagnosis.

## Abstract

Small bowel or mid-gut gastrointestinal (GI) bleeding has been historically difficult to diagnose and is believed to be the main culprit of what was once termed obscure GI bleeding. Small bowel bleeding is difficult to evaluate due to its inaccessibility by direct visualization. Due to recent innovations in diagnostic techniques such as video capsule endoscopy (VCE), deep enteroscopy, and CT enterography, the capability to visualize and diagnose pathologies within the small bowel has improved. One such pathology is neuroendocrine tumors (NETs), which in recent years have overtaken adenocarcinoma as the most common malignancy of the small intestine. Early-stage small bowel neuroendocrine tumors (SBNETs) in the jejunal-ileum are difficult to detect due to their indolent nature and are often found only after they metastasize. We describe a case of small bowel GI bleeding in a functional 90-year-old patient where methodological use of advanced diagnostic modalities with video capsule endoscopy and double balloon enteroscopy helped identify an early-stage SBNET of the jejunal-ileum, leading to timely surgical intervention.

## Linked entities

- **Diseases:** adenocarcinoma (MONDO:0004970)

## Full-text entities

- **Diseases:** malignancy (MESH:D009369), bowel bleeding (MESH:D012778), metastasize (MESH:D009362), adenocarcinoma (MESH:D000230), NETs (MESH:D018358), GI bleeding (MESH:D006471)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12631505/full.md

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Source: https://tomesphere.com/paper/PMC12631505