# Efficacy of left subclavian artery laser in situ fenestration combined with hybrid arch debranching surgery for aortic arch reconstruction in patients with Stanford type A aortic dissection

**Authors:** Qi Zhang, Hao Zhao, Yongqiang Yue, Shuai Zhang, Likun Sun, Peng Xu, Chao Liu, Zhaohui Hua, Zhen Li

PMC · DOI: 10.3389/fcvm.2025.1622468 · 2025-11-06

## TL;DR

A new surgical technique combining laser fenestration and hybrid debranching improves outcomes for aortic dissection patients.

## Contribution

Combining laser fenestration with hybrid debranching for aortic arch reconstruction is shown to reduce complications and improve success rates.

## Key findings

- The ISLF group had shorter operative time and higher LSA reconstruction success.
- LSA complication rates were significantly lower in the ISLF group.
- Five-year survival rates were similar between the two groups.

## Abstract

To investigate the early and mid-term outcomes of in situ laser fenestration (ISLF) of the left subclavian artery (LSA) combined with hybrid aortic arch debranching for aortic arch reconstruction in Stanford type A aortic dissection.

This retrospective study analyzed 57 patients (60+ years) treated from 2018 to 2023. LSA reconstruction-related complications were defined as: anastomotic bleeding, LSA occlusion, stent migration, or fenestration-related endoleak. Patients were divided into ISLF + debranching (n = 29) and debranching-only (n = 28) groups. Outcomes were compared using t-tests and Kaplan–Meier analysis.

The ISLF group had shorter operative time (323.1 ± 10.3 vs. 329.4 ± 7.2 min, P = 0.009) and higher LSA reconstruction success (100% vs. 75%, P = 0.013). LSA complication rates were lower in the ISLF group (3.4% vs. 28.6%, P = 0.025). Five-year survival was similar (79.3% vs. 75.0%, P = 0.575).

ISLF with hybrid debranching improves LSA reconstruction success and reduces complications without affecting survival.

## Full-text entities

- **Diseases:** endoleak (MESH:D057867), bleeding (MESH:D006470), Stanford type A aortic dissection (MESH:D000784), LSA complication (MESH:C000721268)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12631219/full.md

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Source: https://tomesphere.com/paper/PMC12631219