# Clinical applications of resting coronary flow detection via transthoracic echocardiography

**Authors:** Zixuan He, Ruohan Zhao, Xin Zhang, Liqiong Shi, Siyi Zhang, Jia Xu, Yinting Xiong, Qing Lv

PMC · DOI: 10.3389/fcvm.2025.1641896 · 2025-11-06

## TL;DR

This paper reviews how resting coronary blood flow measured by echocardiography can help diagnose and predict outcomes in heart disease.

## Contribution

The paper highlights the clinical utility of non-invasive resting coronary flow assessment using transthoracic echocardiography.

## Key findings

- Resting coronary flow provides hemodynamic and diagnostic insights in cardiovascular diseases.
- Advancements in TTE make coronary flow assessment more practical and non-invasive.
- Transthoracic echocardiography can offer prognostic information for patients with heart conditions.

## Abstract

Beyond being a component of coronary flow velocity reserve, resting coronary blood flow is recognized as a clinically relevant measure, providing hemodynamic, diagnostic, and prognostic information across some cardiovascular diseases. With advancements in high-frequency transducers and imaging protocols, transthoracic coronary artery imaging has become increasingly non-invasive, practical, and useful. This review aims to summarize the clinical value and applications of transthoracic echocardiography (TTE) to assess coronary blood flow at rest.

## Linked entities

- **Diseases:** heart disease (MONDO:0005267)

## Full-text entities

- **Diseases:** cardiovascular diseases (MESH:D002318)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12631198/full.md

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Source: https://tomesphere.com/paper/PMC12631198