Beyond the Brackets: A Case Report of Acute Angioedema Associated With Orthodontic Treatment
Akansha Pandey, Ajit V Parihar, T P Chaturvedi, Dishant Mahajan, Vedita Singh

TL;DR
A 14-year-old girl experienced acute angioedema after orthodontic etchant use, highlighting the risk of allergic reactions to dental materials.
Contribution
Reports a rare case of acute angioedema caused by an orthodontic etchant in a patient with no known allergies.
Findings
Acute angioedema occurred after etching with no prior allergy history.
IV antihistamines and corticosteroids resolved the reaction effectively.
Orthodontic materials can cause hypersensitivity reactions requiring prompt management.
Abstract
This case report highlights a rare incidence of acute angioedema triggered by an etchant during orthodontic treatment. It underscores the potential for commonly used dental materials to provoke allergic reactions. A 14-year-old female patient developed lip swelling, burning sensation, and localized pain shortly after etching. The reaction involved predominantly the upper lip, and the patient had no known history of allergy. Clinical signs included diffuse, non-pitting edematous swelling of the lips without systemic involvement. Acute allergic angioedema was diagnosed based on clinical evaluation. Immediate treatment with IV antihistamines and corticosteroids led to complete resolution. Chemical agents used in orthodontics can trigger hypersensitivity reactions. Early recognition, prompt management, and preventive strategies are essential to ensure patient safety during dental procedures.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsCoagulation, Bradykinin, Polyphosphates, and Angioedema · Autoimmune Bullous Skin Diseases · Drug-Induced Adverse Reactions
