# Prenatally Detected Sub-amniotic Cysts: Are They Significant?

**Authors:** Nikolaos Antonakopoulos, Panagiota Tzela, Georgios Adonakis

PMC · DOI: 10.7759/cureus.94989 · 2025-10-20

## TL;DR

This paper discusses a case of large sub-amniotic cysts found during pregnancy and their implications for fetal health.

## Contribution

The paper presents a case report highlighting the sonographic features and clinical management of sub-amniotic cysts.

## Key findings

- Sub-amniotic cysts can enlarge during pregnancy without causing fetal growth restriction.
- A healthy infant was delivered despite the presence of large sub-amniotic cysts.
- Serial monitoring is recommended for large or multiple sub-amniotic cysts.

## Abstract

We report the case of a gravida 2, para 1 woman in whom multiple relatively large sub-amniotic cysts were identified during a routine second-trimester ultrasound. The lesions progressively enlarged but were not associated with abnormal Doppler findings or fetal growth restriction. A planned cesarean delivery at 37 weeks resulted in the birth of a healthy infant, and the cystic findings corresponded with the placental macroscopic appearance at delivery. This case highlights the sonographic features, differential diagnosis, and clinical implications of sub-amniotic cysts. Although the prognosis is generally favorable, careful serial monitoring is warranted in the presence of large or multiple lesions. Further studies are needed to establish standardized management protocols and evaluate long-term outcomes.

## Full-text entities

- **Diseases:** growth restriction (MESH:D005317), Sub-amniotic Cysts (MESH:D003560)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12629144/full.md

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Source: https://tomesphere.com/paper/PMC12629144