# Reference dosimetry data and machine performance comparison for tomotherapy delivery systems audited by IROC

**Authors:** Paige A. Taylor, Hunter Mehrens, Mallory C. Glenn, Fre'Etta Brooks, Hayden Scott, Lian Duan, Taylor Meyers, Diana Carrasco Rojas, Michael Yang, Paola Alvarez, Jessica Lowenstein, Andrea Molineu, Stephen F. Kry

PMC · DOI: 10.1002/acm2.70390 · Journal of Applied Clinical Medical Physics · 2025-11-18

## TL;DR

This study compares dosimetry measurements across TomoTherapy systems to establish a reference dataset for quality assurance.

## Contribution

The paper provides a dataset of dosimetric properties for TomoTherapy units audited by IROC, enabling performance benchmarking.

## Key findings

- Measurements of PDD and OAF were compared across nine TomoTherapy units.
- The dataset includes mean, standard deviation, and median values for dosimetric properties.
- Results can be used to verify beam model commissioning and QA processes.

## Abstract

The aim of this work was to compare the imaging and radiation oncology core (IROC) on‐site TomoTherapy dosimetry measurement results among institutions and generate a dataset of basic dosimetric properties for TomoTherapy units. Independent ion chamber measurements for nine TomoTherapy units were acquired by IROC physicists between 2008 and 2023. Measurements included percent depth dose (PDD) in a water tank and off axis factors (OAF) in a solid Polystyrene phantom. The independent measurements collected during the on‐site audits for each TomoTherapy system were compared to corresponding TomoTherapy TPS calculations from the institution to assess agreement. Numeric measurement values and comparative ratios are compiled and tabulated according to measurement type (i.e., PDD and OAF). The distribution of the measurements was evaluated, and the mean, standard deviation of the mean, and median values are reported. These data provide an independent guide describing the inherent performance characteristics of TomoTherapy units. Such data may serve as a secondary check for users wishing to verify their beam model commissioning and ongoing quality assurance efforts.

## Full-text entities

- **Chemicals:** water (MESH:D014867), Polystyrene (MESH:D011137)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12626754/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12626754/full.md

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Source: https://tomesphere.com/paper/PMC12626754