# Subjective Well‐Being and Its Predictors in Parkinson's Disease and Dystonia: A Comparative Study

**Authors:** Suzette Shahmoon, Dejan Georgiev, Paul Jarman, Kailash Bhatia, Patricia Limousin, Marjan Jahanshahi

PMC · DOI: 10.1002/mdc3.70141 · Movement Disorders Clinical Practice · 2025-05-30

## TL;DR

This study compares subjective well-being in Parkinson's disease and dystonia patients versus healthy controls, identifying key predictors like mood and personality traits.

## Contribution

The study introduces a novel comparative analysis of subjective well-being dimensions in Parkinson's disease and dystonia, identifying unique predictors for each condition.

## Key findings

- People with Parkinson's disease and dystonia had significantly lower life satisfaction than healthy controls.
- Self-esteem and loneliness were significant covariates for life satisfaction in Parkinson's disease and dystonia.
- Depression was the main predictor of subjective happiness in dystonia, explaining 49% of the variance.

## Abstract

Quality of life (QoL) is a commonly used outcome measure in people with chronic neurological diseases (CND). As valuable as QoL is, it does not take into account aspects of subjective well‐being (SWB) such as subjective happiness, meaning in life, life satisfaction and hope; all constructs that are considered central to well‐being.

The goal was to assess how the different aspects of SWB are altered in Parkinson's disease (PD) and dystonia relative to healthy controls (HCs) and to identify the most important predictors of different dimensions of SWB in PD and dystonia.

Eighty‐two people with PD, 63 with dystonia, and 50 HCs were surveyed using various measures of SWB.

People with PD and dystonia had significantly lower satisfaction with life than HCs, with self‐esteem and loneliness being significant covariates. Although people with PD and dystonia had significantly less meaning in life, they still sought meaning in life as much as HCs. Self‐esteem, resilience and neuroticism were significant covariates for the presence of “meaning in life.” There were no significant group differences in subjective happiness or hope. In people with PD, mood (depression and anxiety), personality traits (extraversion and self‐esteem), disease duration, and pain/discomfort were significant predictors of various measures of SWB. The main significant predictor of SWB in dystonia was depression, which predicted 49% of the variance in subjective happiness.

These results emphasize the importance of SWB as a field of investigation and clinical care in the management of people with PD and dystonia.

## Linked entities

- **Diseases:** Parkinson's disease (MONDO:0005180), dystonia (MONDO:0003441)

## Full-text entities

- **Diseases:** anxiety (MESH:D001007), pain (MESH:D010146), Dystonia (MESH:D004421), depression (MESH:D003866), PD (MESH:D010300), CND (MESH:D002908)

## Full text

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## Figures

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## References

72 references — full list in the complete paper: https://tomesphere.com/paper/PMC12625102/full.md

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Source: https://tomesphere.com/paper/PMC12625102