# Mediating effects of psychological capital on the influencing relationship between social isolation and anxiety symptoms of maintenance hemodialysis patients

**Authors:** Ying Li, Fan Yang, Jianhua Zhang, Meng Xiang, Haibo Wu

PMC · DOI: 10.3389/fpsyg.2025.1550052 · Frontiers in Psychology · 2025-11-04

## TL;DR

This study explores how psychological capital partially mediates the link between social isolation and anxiety in hemodialysis patients.

## Contribution

The novel finding is that psychological capital partially mediates the relationship between social isolation and anxiety symptoms in MHD patients.

## Key findings

- Social isolation is positively correlated with psychological capital and negatively correlated with anxiety symptoms.
- Psychological capital accounts for 7.693% of the total effect between social isolation and anxiety.
- Smoking history, heart failure, and dialysis time are significant factors associated with anxiety in MHD patients.

## Abstract

Limited research has examined the direct or indirect effects of social isolation on anxiety symptoms. This study investigated the mediating effect of psychological capital (PsyCap) on social isolation and anxiety symptoms.

The study included 202 maintenance hemodialysis (MHD) patients from Shanghai Hospital in China. Data collection utilized basic data, social isolation, anxiety self-assessment, and psychological capital questionnaires. Statistical analysis employed PROCESS4.1 and SPSS26.0 for univariate and correlation analyses, with Model 4 being utilized for mediation effect assessment.

Smoking history, heart failure, and dialysis time were identified as significant factors associated with anxiety in MHD patients. Social isolation score is positively correlated with PsyCap (r = 0.442, p < 0.001), and negative correlated with anxiety symptoms (r = −0.786, p < 0.001). The mediating effect of PsyCap accounts for 7.693% of the total effect.

Psychological capital plays a partial mediating role in the relationship between social isolation and anxiety in MHD patients. It is necessary to strengthen the assessment of social isolation in MHD patients to improve PsyCap and reduce the risk of anxiety symptoms.

## Linked entities

- **Diseases:** heart failure (MONDO:0005252)

## Full-text entities

- **Diseases:** anxiety (MESH:D001007), heart failure (MESH:D006333), anxiety symptoms (MESH:D001008)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12624775/full.md

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Source: https://tomesphere.com/paper/PMC12624775