# Single-cell transcriptome profiling reveals altered neural crest cell dynamics and novel biomarkers in EDNRB mutant mice with Hirschsprung's disease phenotype

**Authors:** Minhao Sun, Jafari Halima, Yidan Li, Jiangtian Su, Ge Yang, Jiajun Guo, Qiwen Yang, Ruihua Dang

PMC · DOI: 10.1016/j.gendis.2025.101765 · Genes & Diseases · 2025-07-08

## Full-text entities

- **Genes:** Ednrb (endothelin receptor type B) [NCBI Gene 13618] {aka ET-B, ET-BR, ETR-b, ETb, Sox10m1}
- **Diseases:** Hirschsprung's disease (MESH:D006627)
- **Species:** Mus musculus (house mouse, species) [taxon 10090]

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Source: https://tomesphere.com/paper/PMC12624628