# Takotsubo syndrome triggered by a pleasant emotional event: a case report

**Authors:** Eder Jonathan Amaro-Palomo, Myles Andrew Laurence-Salinas, Santiago Alba-Valencia, Diego Araiza-Garaygordobil

PMC · DOI: 10.47487/apcyccv.v6i3.500 · Archivos Peruanos de Cardiología y Cirugía Cardiovascular · 2025-09-24

## TL;DR

A 53-year-old man developed Takotsubo Syndrome after a joyful emotional event, highlighting that positive stress can also trigger this condition.

## Contribution

This case report documents a rare instance of Takotsubo Syndrome triggered by a positive emotional event, expanding understanding of its triggers.

## Key findings

- A 53-year-old male developed TTS after a joyful emotional event.
- Diagnosis was confirmed via coronary angiography and left ventriculography.
- The case emphasizes the need to consider positive emotional triggers in TTS diagnosis.

## Abstract

Takotsubo Syndrome (TTS) is characterized by transient left ventricular dysfunction, often triggered by emotional or physical stress. While negative emotional events are common triggers, positive emotional events can also induce a rare variant known as Happy Heart Syndrome (HHS). This case report describes a 53-year-old male who presented with acute chest pain following a positive emotional stimulus: a birthday call offering him an opportunity to play with his favorite music group. Initial workup suggested an acute myocardial infarction, but coronary angiography revealed no obstruction. Left ventriculography showed the classic apical ballooning pattern of TTS. The patient was diagnosed with HHS. This case underscores the importance of considering positive emotional triggers in the diagnosis of TTS and highlights the need for further research into its diverse presentations and management strategies.

## Linked entities

- **Diseases:** Takotsubo Syndrome (MONDO:0019018)

## Full-text entities

- **Diseases:** myocardial infarction (MESH:D009203), TTS (MESH:D054549), chest pain (MESH:D002637), HHS (MESH:D017204), left ventricular dysfunction (MESH:D018487)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12624471/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12624471/full.md

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Source: https://tomesphere.com/paper/PMC12624471