# Treatment of Angiomyoblastoma in a Young Lady in Saudi Arabia: A Case Report: Angiomyoblastoma in a Young pLady in Saudi Arabia

**Authors:** Roua Shoub Gbril Ali, Ghadeer Adel Mosfer Alghamdi, Raad Hadi Madkhali, Abdulaziz Saleh Alobaid, Zarqa Saleem

PMC · DOI: 10.31661/gmj.v14i.3861 · Galen Medical Journal · 2025-10-28

## TL;DR

This case report describes a rare benign tumor in a 36-year-old woman in Saudi Arabia, highlighting the importance of accurate diagnosis and surgical treatment.

## Contribution

The paper presents a rare case of angiomyofibroblastoma in Saudi Arabia and emphasizes the need for precise diagnostic methods.

## Key findings

- The tumor was diagnosed as angiomyofibroblastoma after surgical resection and immunohistochemical analysis.
- MRI confirmed complete resection with no recurrence two months post-surgery.
- Accurate diagnosis required differentiating AMFB from similar tumors like angiomyxoma or myxoid liposarcoma.

## Abstract

Background: Angiomyofibroblastoma (AMFB) is a rare, benign soft tissue tumor
that belongs to the mesenchymal tumor category and affects the female
genital tract. Aggressive angiomyxoma, a distinct stroma myxoedematous
mesenchymal tumor with a significant risk of local recurrences, must be
histomorphologically distinguished from AMFB. Radiography and histopathology
are used for accurate diagnosis. The treatment depended on the complete
surgical excision.

Case Presentation: Herein, we presented a case of a 36-year-old female (P3+0)
presented with a left vaginal mass noted two years prior. The radiology
report suggested angiomyxoma or myxoid liposarcoma as possible
differentials. Surgical resection revealed a benign genital stromal tumor,
specifically angiomyofibroblastoma (AMFB). After complete surgical excision,
the immunohistochemical analysis supported the diagnosis of
angiomyofibroblastoma. Two months postoperatively, an MRI Post-resection
images show complete resection with no feasible scar, residual tumour, or
recurrence.

Conclusion: Our case is rare AMFB. AMFB may be missed when diagnosed with
other masses, such as angiomyxoma or myxoid liposarcoma, so we need to do
the necessary tests to diagnose and differentiate AMFB accurately from other
masses. Ultrasound and MRI are initial diagnostic tools, while
histopathology ensures the correct diagnosis. Surgical removal with free
margins remains the appropriate treatment. Long-term follow-up is essential
to monitor for potential recurrence, though AMFB typically carries an
excellent prognosis.

## Linked entities

- **Diseases:** angiomyxoma (MONDO:0006086), myxoid liposarcoma (MONDO:0013280)

## Full-text entities

- **Diseases:** mesenchymal tumor (MESH:C535700), masses (MESH:C536030), tumour (MESH:D009369), angiomyxoma (MESH:D009232), vaginal mass (MESH:D014623), myxoid liposarcoma (MESH:D018208), genital stromal tumor (MESH:D046152), soft tissue tumor (MESH:D012983)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12624247/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12624247/full.md

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Source: https://tomesphere.com/paper/PMC12624247