# Enhanced transoral outlet reduction using endoscopic submucosal dissection and zipper-type suture technique after Roux-en-Y gastric bypass

**Authors:** Davekaran Buttar, Mayank Goyal, Ashwariya Ohri, Barham K. Abu Dayyeh

PMC · DOI: 10.1016/j.vgie.2025.06.005 · VideoGIE · 2025-06-25

## TL;DR

A new minimally invasive technique is introduced to reduce weight regain after gastric bypass surgery by modifying the stomach outlet.

## Contribution

A modified transoral outlet reduction technique combining submucosal dissection and a zipper-style suture is proposed.

## Key findings

- A patient achieved 14% total body weight loss after the modified procedure.
- GERD symptoms were resolved with no adverse events reported.
- The modified technique shows potential for improved durability and outcomes.

## Abstract

Weight regain after Roux-en-Y gastric bypass is common and often linked to anatomical changes such as gastrojejunal anastomosis (GJA) dilation and pouch enlargement. Transoral outlet reduction (TORe) offers a minimally invasive alternative to surgical revision. We present a modified TORe technique incorporating submucosal dissection, argon plasma coagulation, zipper-style GJA suturing, and distal pouch tubularization.

A 53-year-old woman with post-Roux-en-Y gastric bypass weight recurrence and GERD underwent enhanced TORe. The procedure included submucosal dissection of the GJA, argon plasma coagulation, zipper-pattern endoscopic suturing for GJA reduction, and tubularization of the distal gastric pouch.

At 6-month follow-up, the patient achieved 14% total body weight loss and resolution of GERD symptoms. No adverse events occurred.

This modified zipper-TORe approach is safe and efficient and may enhance durability and clinical outcomes.

## Linked entities

- **Diseases:** GERD (MONDO:0007186)

## Full-text entities

- **Diseases:** GERD (MESH:D005764), weight loss (MESH:D015431)
- **Chemicals:** Roux (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12624233/full.md

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Source: https://tomesphere.com/paper/PMC12624233