# Mind–Body Interventions for Prediabetes Management: Traditional Chinese Exercise and Its Dual Effects on Metabolic Control and Psychological Well-Being—A Systematic Review and Meta-Analysis

**Authors:** Yaoming Yang, Ran Chen, Xinbao Wang, Yuqian Yan, Tao Huang, Chunfang Wang, Guoyong Yu

PMC · DOI: 10.1155/jdr/8249301 · Journal of Diabetes Research · 2025-11-10

## TL;DR

This study reviews how traditional Chinese exercises can help manage prediabetes by improving both blood sugar levels and mental health.

## Contribution

The study provides a systematic review and meta-analysis of traditional Chinese exercises' dual effects on metabolic and psychological outcomes in prediabetes.

## Key findings

- TCEs significantly improved fasting blood glucose, insulin resistance, and glycated hemoglobin.
- Psychological benefits were observed across all types of traditional Chinese exercises.
- Baduanjin and Qigong showed the most consistent metabolic improvements, while Taiji had limited evidence.

## Abstract

This study was aimed at evaluating the effectiveness of traditional Chinese exercises (TCEs) in improving both physical and psychological health in individuals with prediabetes.

Randomized controlled trials were systematically searched in the Cochrane Library, PubMed, Web of Science, Embase, China National Knowledge Infrastructure (CNKI), Wanfang, VIP, and the Chinese Biomedical Literature Database (CBM) up to August 28, 2025. Data from 22 trials involving 1854 participants were analyzed using Stata 15.0. The risk of bias was assessed with the Cochrane RoB 2.0 tool.

TCEs significantly improved fasting blood glucose (FBG), insulin resistance, glycated hemoglobin (HbA1c), 2-h postprandial blood glucose (2hPG), and several psychological outcomes compared with controls. Subgroup analyses showed consistent improvements in FBG at 3, 6, and 12 months, although the effect size and heterogeneity varied across time points. HbA1c and 2hPG improved at 3 and 6 months, while fasting insulin changes were significant only at 3 months. Baduanjin and Qigong were most effective for metabolic outcomes, whereas evidence for Taiji was limited and inconclusive, though some studies suggested potential benefits for HbA1c. Psychological benefits were observed across all exercise types.

TCEs may enhance metabolic regulation and psychological well-being in individuals with prediabetes, potentially reducing the risk of progression to Type 2 diabetes. However, due to high heterogeneity and small sample sizes for some outcomes, these findings should be interpreted with caution. Large, well-designed multicenter trials are warranted to confirm these effects.

## Linked entities

- **Diseases:** prediabetes (MONDO:0006920), Type 2 diabetes (MONDO:0005148)

## Full-text entities

- **Genes:** INS (insulin) [NCBI Gene 3630] {aka IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10}
- **Diseases:** Prediabetes (MESH:D011236), Type 2 diabetes (MESH:D003924), insulin resistance (MESH:D007333)
- **Chemicals:** 2hPG (-), glucose (MESH:D005947)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12623101/full.md

## References

54 references — full list in the complete paper: https://tomesphere.com/paper/PMC12623101/full.md

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Source: https://tomesphere.com/paper/PMC12623101