# First isolation of Prototheca bovis from a bottlenose dolphin (Tursiopstruncatus)

**Authors:** Chika Shirakata, Kanon Tsurumi, Koichi Makimura, Rui Kano

PMC · DOI: 10.1016/j.mmcr.2025.100746 · Medical Mycology Case Reports · 2025-10-24

## TL;DR

Prototheca bovis was first isolated from a bottlenose dolphin with digestive issues, marking a new occurrence in dolphin health.

## Contribution

This study reports the first isolation of Prototheca bovis from a dolphin, expanding knowledge on this organism's host range.

## Key findings

- Prototheca bovis was isolated from a bottlenose dolphin with digestive tract abnormalities.
- The dolphin showed candida-like yeasts and mucosal thickening with ulcers in the forestomach.
- This is the first documented case of Prototheca sp. in a marine mammal.

## Abstract

To our knowledge, this is the first report of Prototheca sp. isolated from the digestive tract of a dolphin. A captive-born female bottlenose dolphin (Tursiops truncatus) weighing 165 kg that was housed at Enoshima Aquarium presented with a slightly elevated body temperature and candida-like yeasts in stomach fluid and feces. Gastroscopy revealed cobblestone-like thickening of the mucosa with a few ulcers in the forestomach. Prototheca bovis was isolated from the biopsy specimen of the lesion.

## Linked entities

- **Species:** Tursiops truncatus (taxon 9739)

## Full-text entities

- **Diseases:** ulcers (MESH:D014456)
- **Species:** Tursiops truncatus (Atlantic bottlenose dolphin, species) [taxon 9739], Delphinus delphis (Black Sea dolphin, species) [taxon 9728], Saccharomyces cerevisiae (baker's yeast, species) [taxon 4932], candida [taxon 1535326]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12621472/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12621472/full.md

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Source: https://tomesphere.com/paper/PMC12621472