# MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing

**Authors:** Robinson Vidva, Mir Abbas Raza, Jaswant Prabhakaran, Ayesha Sheikh, Alaina Sharp, Hayden Ott, Amelia Moore, Christopher Fleisher, Hailey Netherton, Evan Goldstein, Pothitos M. Pitychoutis, Tam V. Nguyen, Aaron Sathyanesan

PMC · DOI: 10.1016/j.csbj.2025.01.025 · Computational and Structural Biotechnology Journal · 2025-02-01

## TL;DR

MyVivarium is a low-cost, open-source cloud-based tool for managing lab animal colonies and tracking environmental conditions in real time.

## Contribution

MyVivarium introduces a novel, easy-to-deploy, open-source solution for lab animal colony management with real-time ambient sensing.

## Key findings

- MyVivarium can be deployed to the cloud at a cost comparable to maintaining a lab website.
- The system uses QR codes for efficient, mobile-friendly animal and cage tracking.
- Ambient variables like temperature and humidity are monitored and sent to the database in real time.

## Abstract

Management of research-animal colonies is vital for lab productivity in preclinical research. Labs often rely on inefficient paper-based or spreadsheet-based methods to manage animal colonies. Dedicated software-based solutions are generally expensive and many lack remote access. Currently available open-source alternatives are difficult to implement and deploy. These solutions also do not have the capability to track ambient variables that affect colony well-being. We built MyVivarium, an open-source database management web application to address these gaps. MyVivarium can be easily deployed to the cloud and sustained for a cost comparable to starting and maintaining a lab website. Using MyVivarium, lab members can collaboratively track individual animals within a database. Physical identities of cages map onto the database using QR codes, enabling quick and easy record-keeping on mobile devices. Lab administrators can assign tasks to users with reminders for experiments or cage maintenance. Finally, we designed a low-cost system to sense ambient humidity, temperature, vivarium worker activity, and room illuminance. These data are then sent to MyVivarium in realtime providing information relevant to colony well-being. Taken together, MyVivarium is a novel, open-source, cloud-based application template that provides a low-cost, simple, and efficient way to digitally manage research-animal colonies.

## Full-text entities

- **Genes:** Mr1 (major histocompatibility complex, class I-related) [NCBI Gene 15064] {aka H2ls}, Phpt1 (phosphohistidine phosphatase 1) [NCBI Gene 75454] {aka 1700008C22Rik, PHP, Php14}
- **Diseases:** Down syndrome (MESH:D004314), injuries (MESH:D014947)
- **Chemicals:** Goldstein (-), Pi (MESH:D010716)
- **Species:** Ceratobasidium sp. AG-E (species) [taxon 358989], Rodentia (rodent, order) [taxon 9989], Homo sapiens (human, species) [taxon 9606], Rattus norvegicus (brown rat, species) [taxon 10116], Mus musculus (house mouse, species) [taxon 10090]

## Full text

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## Figures

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## References

45 references — full list in the complete paper: https://tomesphere.com/paper/PMC12621272/full.md

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Source: https://tomesphere.com/paper/PMC12621272