# Cryosurgery in oral lesions

**Authors:** Eleni Georgakopoulou, Panagiota Loumou, Dimitrios Sgouros, Akhilanand Chaurasia, Antonios Panagiotopoulos

PMC · DOI: 10.4317/jced.63133 · Journal of Clinical and Experimental Dentistry · 2025-10-01

## TL;DR

Cryosurgery, using extreme cold, is an effective treatment for oral lesions and has been widely used since the 1960s.

## Contribution

The paper highlights cryosurgery's application in oral mucosal diseases as an alternative therapy.

## Key findings

- Cryosurgery has been used in multiple medical fields since the 1960s.
- It is effective for treating benign, precancerous, and malignant oral lesions.
- Cryosurgery is considered a versatile alternative therapy for oral mucosal diseases.

## Abstract

Cryosurgery is a treatment method that employs extremely low temperatures to address various diseases. Since the early 1960s, liquid nitrogen has been utilized in dermatology, oral surgery, ophthalmology, gynecology, urology, cardiology, and internal organ surgery. It is the preferred treatment for numerous skin conditions due to its versatility in addressing benign, precancerous, and malignant diseases.

The application of cryosurgery as a therapeutic approach for oral mucosal diseases has been shaped by the treatment of analogous dermatological conditions. Considering the potential of cryosurgery applications, it has been utilized as an alternative therapy for various oral lesions.

Key words:Cryosurgery, Oral lesions, Liquid nitrogen, Oral mucosal diseases, Cryotherapy mechanisms, Cryogens, Oral medicine.

## Linked entities

- **Chemicals:** liquid nitrogen (PubChem CID 947)

## Full-text entities

- **Diseases:** Oral lesions (MESH:D009059), diseases (MESH:D004194), Oral (MESH:D020820), precancerous, (MESH:D011230)
- **Chemicals:** nitrogen (MESH:D009584)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12621005/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12621005/full.md

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Source: https://tomesphere.com/paper/PMC12621005