# Case Report: Bilateral testicular teratoma in an infant with torsion of an intra-abdominal testis and contralateral testicular teratoma

**Authors:** Chaoyang Hua, Hongjie Fan, Zhan Guo, Xing Li, Yanfang Yang, Jianpeng Bi

PMC · DOI: 10.3389/fped.2025.1680506 · Frontiers in Pediatrics · 2025-11-03

## TL;DR

This case report describes a rare instance of bilateral testicular teratomas in an infant, highlighting the importance of early diagnosis and fertility-preserving surgery.

## Contribution

The report emphasizes the clinical management of torsion in an intra-abdominal testis with contralateral teratoma in infants.

## Key findings

- Bilateral mature teratomas in an infant were confirmed through laparoscopy and histopathology.
- Testis-sparing surgery preserved fertility potential in the contralateral testis.
- Postoperative monitoring showed no recurrence at 6 months with normalized alpha-fetoprotein levels.

## Abstract

Bilateral testicular tumors in infants are extremely rare. This case report describes synchronous bilateral mature teratomas complicated by torsion of an intra-abdominal undescended testis (IAT), and underscores the clinical importance of early diagnosis, timely surgical intervention, and fertility-preserving management, providing valuable reference for future cases.

A 3-month-old boy presented with an empty right hemiscrotum. Imaging revealed a right intra-abdominal mass (22.8 × 15.9 × 21.3 mm) and left testicular lesion (7.1 × 3.9 × 7.0 mm). Serum alpha-fetoprotein was within normal limits for age, suggesting benign disease. Laparoscopy confirmed a torsed necrotic right testicular mass, managed by orchiectomy. Left testis-sparing surgery excised a separate tumor. Histopathology confirmed bilateral mature teratoma. Hormonal profiles, including testosterone (0.81 ng/mL) and follicle-stimulating hormone (3.74 mIU/mL), as well as karyotype (46,XY), were normal. No additional therapy was required, as mature teratomas are benign. Postoperative alpha-fetoprotein levels normalized, with no recurrence at 6-month follow-up. Parental education regarding testicular examination is important for early detection of future abnormalities.

Tumors associated with intra-abdominal undescended testes warrant urgent intervention due to torsion risk. Surgery preserving testicular tissue is recommended for bilateral benign teratomas to maintain fertility. Serial alpha-fetoprotein monitoring and ultrasound surveillance are essential postoperatively.

## Linked entities

- **Diseases:** testicular teratoma (MONDO:0018193)

## Full-text entities

- **Genes:** AFP (alpha fetoprotein) [NCBI Gene 174] {aka AFPD, FETA, HPAFP}
- **Diseases:** benign teratomas (MESH:D013724), testicular teratoma (MESH:C562472), testicular lesion (MESH:D013733), IAT (MESH:D003456), necrotic (MESH:D009336), intra-abdominal mass (MESH:D000082122), testicular tumors (MESH:D013736), torsion (MESH:D050723), Tumors (MESH:D009369)
- **Chemicals:** testosterone (MESH:D013739)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12620381/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12620381/full.md

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Source: https://tomesphere.com/paper/PMC12620381