# Shewanella algae-induced relapsing peritoneal dialysis-associated peritonitis: a case report

**Authors:** Jiawei Tang, Nana Luo, Yiming Zhang, Chen Wang

PMC · DOI: 10.3389/fmed.2025.1636954 · Frontiers in Medicine · 2025-11-03

## TL;DR

A patient with peritoneal dialysis developed recurring peritonitis caused by Shewanella algae, which was successfully treated with high-concentration gentamicin.

## Contribution

Demonstrates the effectiveness of high-concentration antibiotic lock therapy in treating relapsing Shewanella algae peritonitis.

## Key findings

- Shewanella algae infection caused recurring peritoneal dialysis-related peritonitis.
- High-concentration gentamicin sulfate via intra-catheter instillation resolved the infection without recurrence.
- Antibiotic lock therapy is effective against biofilm-associated Shewanella algae infections.

## Abstract

This article presents a case report of relapsing peritoneal dialysis-associated peritonitis caused by Shewanella algae. The patient has experienced relapsing peritonitis, accompanied by abdominal pain and cloudy peritoneal dialysis fluid. Ascites culture revealed an infection with Shewanella algae. Treatment with high-concentration gentamicin sulfate via intra-catheter antibiotic instillation led to complete resolution of the infection, with no recurrence observed. Shewanella algae-induced peritoneal dialysis-related peritonitis is rare, and its relapsing nature may be attributed to bacterial biofilm formation within the catheter. High-concentration antibiotic lock therapy demonstrated efficacy in eradicating the infection. This report explores the efficacy and application value of antibiotic lock therapy in managing relapsing Shewanella algae-associated peritoneal dialysis-related peritonitis.

## Linked entities

- **Chemicals:** gentamicin sulfate (PubChem CID 6419933)
- **Species:** Shewanella algae (taxon 38313)

## Full-text entities

- **Diseases:** infection (MESH:D007239), peritonitis (MESH:D010538), abdominal pain (MESH:D015746)
- **Chemicals:** gentamicin sulfate (MESH:D005839)
- **Species:** Homo sapiens (human, species) [taxon 9606], Shewanella algae (species) [taxon 38313]

## Full text

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## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12620267/full.md

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Source: https://tomesphere.com/paper/PMC12620267