# A case report of pulmonary adenocarcinoma with thoracic duct lymphangioma and chylothorax

**Authors:** Zichun Tang, Rui Xu, Peng Dai, Juncheng Chen, Zongwei Xiao

PMC · DOI: 10.3389/fmed.2025.1712061 · Frontiers in Medicine · 2025-11-03

## TL;DR

This case report describes a rare instance of lung cancer combined with a lymphangioma and chylothorax, highlighting the challenges in diagnosis and treatment.

## Contribution

The paper presents a rare coexistence of thoracic duct lymphangioma, chylothorax, and lung adenocarcinoma, offering clinical insights for managing such complex cases.

## Key findings

- Thoracic duct lymphangioma coexisting with lung adenocarcinoma is clinically rare.
- Meticulous intraoperative dissection is crucial to prevent thoracic duct injury and chylothorax.
- Early intervention for postoperative chylothorax is essential for improving prognosis.

## Abstract

Thoracic duct lymphangioma, a rare benign lesion, requires surgical resection. The thoracic duct is highly susceptible to damage during surgery, leading to chylothorax. Therefore, meticulous exploration and gradual dissection are crucial to minimizing this risk. Thoracic duct lymphangioma coexisting with lung adenocarcinoma is clinically rare. Preoperative imaging evaluation should be comprehensive, intraoperative meticulous dissection is crucial to reduce the likelihood of thoracic duct injury, and early intervention for postoperative chylothorax is essential to improve prognosis. This case aims to investigate the clinical characteristics, diagnostic and therapeutic strategies, and prognosis of lung adenocarcinoma complicated with thoracic duct lymphangioma and chylothorax. This case report aims to provide clinical reference for managing such complex cases.

## Full-text entities

- **Diseases:** chylothorax (MESH:D002916), thoracic duct injury (MESH:D013898), Thoracic duct lymphangioma (MESH:D008202), lung adenocarcinoma (MESH:D000077192), pulmonary adenocarcinoma (MESH:D000230)

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12620216/full.md

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Source: https://tomesphere.com/paper/PMC12620216