# Early Multidisciplinary Rehabilitation Improves Swallowing and Speech Function in a Patient With Amyotrophic Lateral Sclerosis

**Authors:** Yue Hu, Yun Lu, Danmei Lan

PMC · DOI: 10.1002/ccr3.71486 · Clinical Case Reports · 2025-11-16

## TL;DR

Early multidisciplinary rehabilitation significantly improved swallowing and speech in a patient with ALS, offering hope for better management of the disease.

## Contribution

Demonstrates the effectiveness of early multidisciplinary rehabilitation in improving functional outcomes for ALS patients.

## Key findings

- The patient showed significant improvement in swallowing and speech after 45 days of rehabilitation.
- Non-motor symptoms like anxiety and depression were alleviated through the intervention.
- The patient retained the ability to consume soft foods two years after treatment.

## Abstract

Amyotrophic lateral sclerosis (ALS) is a chronic, progressive neurodegenerative disease for which there is a lack of effective treatment. This case report describes a 49‐year‐old male with ALS who presented with dysphagia, dysarthria, dyskinesia, sleep disorders, anxiety, and depression. Following 45 days of early multidisciplinary rehabilitation, the patient demonstrated significant improvement in swallowing and speech function, alleviation of non‐motor symptoms, and maintenance of motor function. Notably, he retained the ability to consume soft foods at a two‐year follow‐up. This case highlights the vital role of early multidisciplinary rehabilitation in the comprehensive management of ALS.

## Linked entities

- **Diseases:** Amyotrophic lateral sclerosis (MONDO:0004976), anxiety (MONDO:0005618), depression (MONDO:0002050)

## Full-text entities

- **Diseases:** ALS (MESH:D000690), dysarthria (MESH:D004401), dysphagia (MESH:D003680), neurodegenerative disease (MESH:D019636), depression (MESH:D003866), dyskinesia (MESH:D004409), sleep disorders (MESH:D012893), anxiety (MESH:D001007)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12620117/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12620117/full.md

## References

38 references — full list in the complete paper: https://tomesphere.com/paper/PMC12620117/full.md

---
Source: https://tomesphere.com/paper/PMC12620117