# Giant Aneurysm of the Left Main Coronary Artery: A Case Report

**Authors:** Istria Barros, Alberto Navarro, Emilio Herrera, Juan Senior

PMC · DOI: 10.7759/cureus.94821 · Cureus · 2025-10-17

## TL;DR

This case report describes a rare giant aneurysm in the left main coronary artery of a young patient successfully treated with conservative therapy.

## Contribution

The novelty lies in demonstrating successful non-surgical management of a giant left main coronary artery aneurysm.

## Key findings

- A young patient with a giant LMCA aneurysm was managed with conservative therapy.
- The patient remained asymptomatic after six months without surgical or percutaneous intervention.
- The case highlights the need for individualized care and further research in managing giant CAAs.

## Abstract

Giant coronary artery aneurysm (CAA) is a rare and often underreported condition, most frequently associated with atherosclerosis but also linked to congenital, inflammatory, and connective tissue disorders. Unlike typical atherosclerotic disease, there is limited evidence regarding the most effective diagnostic tools, treatment options, and prognostic implications for patients with giant CAAs.

The left main coronary artery (LMCA) is an especially uncommon location, where management decisions can be particularly complex due to the lack of established guidelines. We present the case of a young patient with a giant aneurysm of the LMCA who was successfully treated with conservative medical therapy and remained asymptomatic after six months of follow-up without surgical or percutaneous intervention. This report highlights the challenges in choosing appropriate management strategies for giant CAAs and emphasizes the importance of individualized, patient-centered care. It also underscores the need for further studies to develop evidence-based recommendations for diagnosing and treating this rare but clinically significant condition.

## Linked entities

- **Diseases:** atherosclerosis (MONDO:0005311), connective tissue disorders (MONDO:0003900)

## Full-text entities

- **Diseases:** congenital, inflammatory, and connective tissue disorders (MESH:D009372), atherosclerosis (MESH:D050197), Aneurysm (MESH:D000783), CAA (MESH:D003323)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12620032/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12620032/full.md

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Source: https://tomesphere.com/paper/PMC12620032