# Percutaneous Versus Open Management of Thoracic and Lumbar Hyperostotic Fractures: A Case-Control Study

**Authors:** Mark Lawlor, Mina Botros, Clarke Cady-McCrea, Paul T Rubery, Emmanuel N Menga, Robert Molinari, Mark Ehioghae, Lancelot A Benn, Kevin Yoon, Addisu Mesfin

PMC · DOI: 10.7759/cureus.94737 · Cureus · 2025-10-16

## TL;DR

This study compares minimally invasive and open surgery for spine fractures in patients with hyperostotic spine conditions, finding that the minimally invasive approach has benefits like less blood loss and shorter surgery time.

## Contribution

The study provides new comparative evidence on outcomes of minimally invasive versus open surgical techniques for thoracolumbar fractures in hyperostotic spine patients.

## Key findings

- Minimally invasive stabilization resulted in significantly lower blood loss compared to open surgery.
- Operative time was significantly shorter with minimally invasive stabilization.
- Fewer levels of instrumentation were required in the minimally invasive group.

## Abstract

Background

This study aims to examine the surgical outcomes and complications associated with minimally invasive stabilization using percutaneous pedicle screws (MIS-PPS) versus open surgical management (OSM) among patients with spine fractures in the setting of hyperostotic spine diagnosis.

Methodology

This retrospective, case-control study was conducted at a single Level I Trauma Center, including 30 consecutive patients (nine ankylosing spondylitis patients and 21 diffuse idiopathic skeletal hyperostosis patients) who underwent surgery for thoracolumbar extension-distraction fractures. Collected data included patient demographics, comorbidities, injury mechanism, spine region, fracture level, and intraoperative and postoperative complications. Continuous variables included age, body mass index, estimated blood loss, operative time, number of levels instrumented, and length of stay.

Results

Between 2002 and 2020, 15 patients underwent MIS-PPS (3 females, 12 males, average age of 75.3 years) and 15 underwent OSM (3 females, 12 males, average age of 73.6 years). The MIS-PPS group had significantly lower blood loss (95 ± 31.6 mL vs. 643.3 ± 534.4 mL; p < 0.001) and shorter operative time (130.7 ± 36.4 minutes vs. 208.7 ± 41.8 minutes; p < 0.001). They also required fewer levels of instrumentation (5.2 vs. 6.8; p < 0.001). There were no significant differences in postoperative infection rates, epidural hematomas, or implant revisions between the groups.

Conclusions

MIS-PPS provides the benefits of reduced blood loss, shorter operative time, and fewer levels of instrumentation compared to OSM, with no significant differences in postoperative complications.

## Linked entities

- **Diseases:** ankylosing spondylitis (MONDO:0005306), diffuse idiopathic skeletal hyperostosis (MONDO:0007127)

## Full-text entities

- **Diseases:** Hyperostotic Fractures (MESH:C537115), diffuse idiopathic skeletal hyperostosis (MESH:D004057), PPS (MESH:C562509), MIS- (MESH:C000718087), blood loss (MESH:D016063), distraction fractures (MESH:C538521), hematomas (MESH:D006406), spine fractures (MESH:D000092443), Trauma (MESH:D014947), ankylosing spondylitis (MESH:D013167), fracture (MESH:D050723), infection (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC12619663/full.md

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Source: https://tomesphere.com/paper/PMC12619663