# An osteoporosis course as a separate component of problem-based learning

**Authors:** Iva Hoffmanová, Valér Džupa, Petr Waldauf, Robert Grill, Václav Báča, Muhammad Abbas Abid, Muhammad Abbas Abid, Muhammad Abbas Abid

PMC · DOI: 10.1371/journal.pone.0336915 · 2025-11-14

## TL;DR

Medical students who took an optional osteoporosis course using problem-based learning scored higher on tests than those who only completed the mandatory curriculum.

## Contribution

This study demonstrates the effectiveness of problem-based learning in improving osteoporosis knowledge among medical students.

## Key findings

- Students in the elective osteoporosis course scored 6.7 points higher on average than the control group (p < 0.001).
- Students in the second elective course scored 3.5 points higher on average than the control group (p = 0.006).
- Problem-based learning led to significantly better understanding of osteoporosis-related topics.

## Abstract

The objective was to compare the extent of acquired knowledge regarding osteoporosis-related issues in a group of medical students who successfully completed an optional “Elective Osteoporosis Course” based on problem-based learning, and a group of medical students who completed only the mandatory curriculum.

Study group I was comprised of 25 fourth-year students who successfully completed the Elective Osteoporosis Course I (focused on pathophysiology, diagnostics, and pharmacological treatment), while control group I was comprised of 25 fifth-year students who successfully completed only all required fourth- and fifth-year courses, but did not participate in the elective Osteoporosis I course. Study group II was comprised of 27 fourth-year students who successfully completed the Elective Osteoporosis Course II (focused on treatment of osteoporotic fractures), while control group II was comprised of 24 sixth-year students who were preparing for final exams in surgical disciplines, but did not participate in the Elective Osteoporosis Course II. The groups were compared using a linear regression model with robust estimation of standard errors using Stata 13.1. A p-value < 0.05 was considered statistically significant.

Study Group I scored, on average, 6.7 points higher than Control Group I on the multiple-choice test (scale –16 to +21). Study Group II scored, on average, 3.5 points higher than Control Group II on the multiple-choice test (scale –21 to +28). Both differences were statistically significant (p < 0.001, R2 = 0.64, 95% CI: 5.2–8.1; p = 0.006, R2 = 0.15, 95% CI: 1.1–5.9; respectively).

Results demonstrated a greater understanding in students who participated in problem-based learning medical studies relative to those who completed only the mandatory curriculum.

## Linked entities

- **Diseases:** osteoporosis (MONDO:0005298)

## Full-text entities

- **Diseases:** osteoporotic fractures (MESH:D058866), Osteoporosis (MESH:D010024)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12617839/full.md

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Source: https://tomesphere.com/paper/PMC12617839