# The Relationship Between Psychedelic Use and Positive Adult Development in Emerging Adulthood: An Integrative Review

**Authors:** Jake Payne, Oliver Robinson, Kevin St. Arnaud, Jacob S. Aday, Melissa Warner, Chris Ludlow, Greg Murray

PMC · DOI: 10.1002/brb3.71043 · 2025-11-14

## TL;DR

This review explores how psychedelic use in young adults may influence their personal growth and development across five key life areas.

## Contribution

The paper introduces a novel framework linking psychedelic use to emerging adult developmental trajectories.

## Key findings

- Classic psychedelics may support positive developmental changes in emerging adults.
- Potential benefits include increased openness, self-awareness, and ethical growth.
- The review identifies five developmental pathways influenced by psychedelic use.

## Abstract

Preliminary evidence suggests that classic psychedelics may exert lasting positive effects on individuals’ mood, cognition, and personality, but little is known about how these effects may differ across the lifespan. Emerging adulthood (18–29) is a critical developmental stage in which individuals transition from dependence on community institutions toward full independence. It is a time when psychedelic experimentation is common, and psychedelics could have distinctive psychological impacts during this phase, although the developmental significance of such effects remains largely untested. This integrative review offers a framework to generate hypotheses regarding possible ways that psychedelic use may positively interact with emerging adult development. Here, we review pathways by which classic psychedelics may facilitate emerging adults’ positive orthogenetic, veridical‐epistemic, eudaimonic, relational, and ethical developmental trajectories through changes in personality trait openness, belief systems, self‐insight, and social concern. Finally, we offer future research directions and discuss key challenges for research into studying the developmental impact of classic psychedelic use in emerging adulthood.

This integrative review explores how classic psychedelic use might broadly be associated with aiding and/or posing risks to emerging adult development along five possible developmental trajectories: orthogenetic, eudaimonic, veridical‐epistemic, relational, and ethical.

## Full-text entities

- **Genes:** HTR2A (5-hydroxytryptamine receptor 2A) [NCBI Gene 3356] {aka 5-HT2A, HTR2}
- **Diseases:** insanity (MESH:D009494), confusion (MESH:D003221), alcohol use disorder (MESH:D000437), schizophrenia spectrum disorders (MESH:D019967), impaired cognitive control (MESH:D003072), death (MESH:D003643), HPPD (MESH:C535473), mood, anxiety, and substance use disorders (MESH:D001008), paranoia (MESH:D010259), depression (MESH:D003866)
- **Chemicals:** LSD (MESH:D008238), psilocybin (MESH:D011562), MDMA (MESH:D018817), HPPD (-), cocaine (MESH:D003042), alcohol (MESH:D000438), substance (MESH:C012600), DMT (MESH:D004130), mescaline (MESH:D008635), heroin (MESH:D003932)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12617272/full.md

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Source: https://tomesphere.com/paper/PMC12617272