# Feasibility and acceptability of self-testing for COVID-19 in Ethiopia: a mixed-methods study

**Authors:** I. Mitiku, S. Keller, A. Abera, H. Hailu, Y. Demissie, D. Melese, L. Chala, N. Madden, R. Powers, C. Mulder, R. Peregrino, A. Bedru, I. Spruijt

PMC · DOI: 10.5588/ijtldopen.24.0075 · 2025-11-12

## TL;DR

This study shows that self-testing for COVID-19 is widely accepted and feasible in Ethiopia when supported with proper education and resources.

## Contribution

The study provides evidence for the feasibility and acceptability of self-testing for COVID-19 in Ethiopia, highlighting key factors for successful implementation.

## Key findings

- 94.2% of invited clients accepted and performed self-testing for COVID-19.
- 73.7% of clients reported they would likely use self-testing in the future.
- Higher perceived infection risk and education level predicted future self-test use.

## Abstract

COVID-19 self-testing can enhance early detection to prevent disease transmission. We assessed the feasibility and acceptability of COVID-19 self-testing in Ethiopia to inform the development of national self-testing guidelines.

We conducted a mixed-methods study and invited clients presenting to health facilities with COVID-19 symptoms or considered high risk for infection for rapid antigen detection (Ag-RDT) self-testing, using nasal swabs. We described client characteristics, self-test, and survey results and used logistic regression to determine predictors for the likeliness of future self-test use. We conducted semi-structured interviews with 13 clients, 8 health workers, and 8 decision makers and used a thematic analysis approach.

Of 359 invited clients, 338 (94.2%) accepted and performed COVID-19 self-testing. 79.9% clients experienced self-testing as very easy and 73.7% reported likeliness of future self-test use, which was predicted by higher perceived risk of infection (adjusted odds ratio [AOR]: 2.75; 95% confidence interval [CI]: 1.02–7.45) and higher educational level (AOR: 5.45; 95% CI: 1.94–15.28). Interviewees perceived self-testing acceptable and feasible if it is available, affordable, and supported by culturally and linguistically sensitive video and written instruction materials.

COVID-19 self-testing is acceptable and feasible if implementation is accompanied by educational campaigns to empower clients to conduct self-testing.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), infection (MESH:D007239)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12617086/full.md

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Source: https://tomesphere.com/paper/PMC12617086