The association between Chinese visceral adiposity index and hypertension among middle-aged and older population: a cross-sectional study based on CHARLS

TL;DR

This study finds that higher Chinese Visceral Adiposity Index is linked to increased hypertension risk in middle-aged and older Chinese adults.

Contribution

The study identifies CVAI as a potential biomarker for hypertension risk in a Chinese population.

Findings

High CVAI is significantly associated with hypertension (OR = 1.967, 95% CI: 1.781, 2.172).

The risk of hypertension increases with higher CVAI (trend test p < 0.001).

Women and non-smokers show a stronger association between CVAI and hypertension.

Abstract

In recent years, obesity has become a serious public health issue. This study aims to investigate the association between the Chinese Visceral Adiposity Index (CVAI) and hypertension among the middle-aged and older population in China.

Data from the China Health and Retirement Longitudinal Study (CHARLS) 2015 wave were used. A 3-knot restricted cubic spline (RCS) was employed to analyze the dose-response relationship between CVAl and hypertension. Logistic regression model was used to explore the association between CVAI and hypertension, adjusting for confounding factors including age, sex, education level, smoking, alcohol consumption, body mass index (BMI), diabetes, hyperlipidemia, and heart disease.

A total of 8,787 individuals were included in the study with a hypertension prevalence of 27.89%. A significant association between CVAI and hypertension was observed. Compared to those in the low CVAI category, hypertension was significantly associated with individuals in the high CVAI category in logistic regression (OR adjusted for confounding factors =1.967, 95% CI: 1.781, 2.172). The results showed that the risk of hypertension significantly increased with higher CVAI (trend test p < 0.001). Additionally, subgroup analyses demonstrated a stronger association between CVAI and hypertension among women (OR = 2.5, 95% CI: 2.18–2.88; P for interaction <0.001) and non-smokers (OR = 2.44, 95% CI: 2.14–2.78; P for interaction = 0.001).

CVAI may therefore potentially serve as a useful biomarker for identifying individuals at higher risk, and controlling visceral adiposity accumulation may be a potential target for the prevention and treatment of hypertension.

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