# Non-resolving, Progressive, Non-ketotic Hyperglycemic Hemichorea-Hemiballismus Syndrome in an Elderly Male

**Authors:** Akash Chandani, Cyrine Cunanan, Sumathi Krishnan, Omar Rage

PMC · DOI: 10.7759/cureus.94603 · 2025-10-14

## TL;DR

An elderly man with diabetes developed involuntary movements due to high blood sugar, which improved with treatment.

## Contribution

This case emphasizes the role of metabolic factors in hemichorea-hemiballismus among elderly patients.

## Key findings

- Hyperdensity in the right basal ganglia was observed in an elderly male with T2DM and involuntary movements.
- Symptoms resolved with glycemic control and neuroleptic treatment.
- The case underscores the importance of metabolic management in neurological conditions.

## Abstract

Non-ketotic hyperglycemic hemichorea-hemiballismus syndrome is a rare neurological condition associated with hyperglycemia from uncontrolled diabetes mellitus. We present a case of a male patient in his late 80s with a background of T2DM who presented with a new onset of progressive involuntary movements involving the left side of his body. Imaging revealed hyperdensity in the right basal ganglia, suggestive of non-ketotic hyperglycemic hemichorea. Management included glycemic control and neuroleptic treatment, with resolution of symptoms in most cases. This case highlights the importance of considering metabolic causes of hemichorea-hemiballismus in elderly patients, glycemic control, and the correlation of these factors with quality of life.

## Linked entities

- **Diseases:** T2DM (MONDO:0005148), diabetes mellitus (MONDO:0005015)

## Full-text entities

- **Diseases:** Hyperglycemic Hemichorea-Hemiballismus Syndrome (MESH:D020820), hyperglycemic (MESH:D006944), uncontrolled diabetes mellitus (MESH:D003920), hyperglycemia (MESH:D006943), neurological condition (MESH:D019636)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12615992/full.md

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Source: https://tomesphere.com/paper/PMC12615992