# A 76-year-old male with abdominal cutaneous nerve entrapment syndrome: a case report

**Authors:** Karolina Kalanj, Matija Herceg, Antonio Ivanac, Sara Kalanj, Mirta Peček, Ana Brundula

PMC · DOI: 10.3389/fpain.2025.1588410 · 2025-10-31

## TL;DR

This case report describes a 76-year-old man with abdominal pain caused by a nerve entrapment condition that was correctly diagnosed and treated.

## Contribution

The paper presents the first documented case where interventional treatment combined with external factors aided in nerve repair for ACNES.

## Key findings

- ACNES can be misdiagnosed but is a more common cause of abdominal pain than previously thought.
- Carnett's sign was used to confirm the diagnosis in this patient after other tests were normal.
- Interventional treatment combined with exogenous factors may help repair nerve damage in ACNES.

## Abstract

Abdominal pain represents a frequent presenting symptom in emergency departments, with up to 20% of patient visits involving abdominal and/or flank pain. Recently published studies indicate that anterior cutaneous nerve entrapment syndrome (ACNES) is a more common cause of these symptoms than previously believed, with up to 2% of patients presenting to the emergency department at teaching hospitals being ultimately diagnosed with the condition. Importantly, ACNES is often misdiagnosed as another cause of abdominal pain. We present a 76-year-old patient whose a chief complaint was persistent abdominal pain localized to the right side of the umbilicus over a 6-week period, associated with a burning sensation of the skin. Following unremarkable laboratory, imaging, and endoscopy findings, the diagnosis of ACNES was confirmed with simple Carnett's sign. This is the first documented report to highlight that interventional treatment when combined with exogenous factors can contribute to the repair of nerve damage.

## Linked entities

- **Diseases:** anterior cutaneous nerve entrapment syndrome (MONDO:0018873), ACNES (MONDO:0018873)

## Full-text entities

- **Diseases:** nerve damage (MESH:D000080902), Abdominal pain (MESH:D015746), ACNES (MESH:D009408)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12615463/full.md

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Source: https://tomesphere.com/paper/PMC12615463