Severe tophaceous gout in the setting of myelofibrosis: A clinical challenge
Nicole Chin, Aidan Megally, Omar Zahra, Akshita Gorantla, Shravika Talla, Emad Allam
TL;DR
A patient with myelofibrosis presented with symptoms resembling infection, but was found to have severe gout, highlighting a rare clinical scenario.
Contribution
Highlights an atypical presentation of tophaceous gout in a patient with myelofibrosis.
Findings
Imaging suggested infection in a patient with myelofibrosis.
Surgery revealed extensive tophaceous gout instead of infection.
This case emphasizes the need to consider gout in myelofibrosis patients with similar symptoms.
Abstract
We illustrate a case of a patient with a history of myelofibrosis, presenting with a clinical picture of presumed infection. Imaging revealed apparent fluid collections and erosions in the ankle/foot, supporting the clinical suspicion of infection. However, operative findings revealed extensive tophaceous gout, likely a consequence of long-standing myelofibrosis. It is important to be aware of this atypical presentation of gout in patients with myelofibrosis.
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Taxonomy
TopicsMyeloproliferative Neoplasms: Diagnosis and Treatment · Gout, Hyperuricemia, Uric Acid · Hematological disorders and diagnostics