Bringing credibility to observational research in critical care: the case of target trial emulation designs

Sérgio Renato da Rosa Decker; Ary Serpa

PMC · DOI:10.62675/2965-2774.20250142·August 8, 2025

Bringing credibility to observational research in critical care: the case of target trial emulation designs

Sérgio Renato da Rosa Decker, Ary Serpa

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Abstract

Linked entities

Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.

Species1

Homo sapiens(human · species)

Chemicals2

dexmedetomidine oxygen

Diseases7

critically ill cancer acute respiratory failure coronary heart disease agitation death COVID-19

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Taxonomy

TopicsMeta-analysis and systematic reviews · Sepsis Diagnosis and Treatment · Cardiac, Anesthesia and Surgical Outcomes