# Fournier’s gangrene as initial presentation of rectal cancer

**Authors:** Saúl Sánchez Iglesias, Cristina de la Cruz Cuadrado, Julián de Pedro Conal

PMC · DOI: 10.1093/jscr/rjaf915 · 2025-11-13

## TL;DR

A 47-year-old man presented with Fournier’s gangrene, which was later found to be the first sign of early-stage rectal cancer.

## Contribution

This case highlights the rare presentation of rectal cancer as Fournier’s gangrene in a young patient with an early pathological stage.

## Key findings

- Fournier’s gangrene can be the initial manifestation of rectal cancer in young patients.
- Despite severe clinical presentation, the cancer was diagnosed at an early stage (pT2N0).
- Early multidisciplinary evaluation is crucial in such cases for better outcomes.

## Abstract

Fournier’s gangrene is a necrotizing fasciitis of the perineum that can occur due to a loss of integrity of the gastrointestinal or urethral mucosa. Its appearance as the debut of a perforated rectal neoplasm is unusual, more uncommon in young patients, leading to an advanced stage of the disease. Therefore, we present the case of a 47-year-old male with Fournier’s gangrene as the debut of a rectal cancer that, despite severe presentation, the pathological stage was early (pT2N0), highlighting the importance of considering neoplastic etiology in perineal gangrene and the need for an early multidisciplinary approach.

## Linked entities

- **Diseases:** Fournier’s gangrene (MONDO:0043352), rectal cancer (MONDO:0006519)

## Full-text entities

- **Diseases:** Fournier's gangrene (MESH:D018934), rectal cancer (MESH:D012004), gangrene (MESH:D005734), fasciitis (MESH:D005208)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12614920/full.md

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Source: https://tomesphere.com/paper/PMC12614920